Recently, detection of seismic electric signals (SESs) in telluric current data (TCD) observed using the VAN method has attracted notice for short-term earthquake prediction. However, since most of the TCD collected in Japan is affected by train noise, detecting SESs in TCD itself is an extremely arduous job. The goal of this research is to derive a method for detecting SESs, which is difficult...

Despite significant progress in the past 20 years, graft-versus-host disease (GVHD) remains a significant cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). T-cell depletion (TCD) of the donor graft offers the potential for prevention of GVHD without the morbidity associated with immunosuppressive drugs such as methotrexate and cyclosporine. Most e...

Transcranial Doppler (TCD) is widely used to investigate the effects of anesthetic drugs on cerebral blood flow. Its repeatability and non-invasivity makes it an ideal, first choice method. Anesthesia providers are required to be conscious of the cerebral hemodynamic effects of drugs given in their practice, especially in neurosurgery and in subjects with impaired brain functions. The purpose o...

Takayasu's arteritis is a disease that affects large vessels and may cause neurological symptoms either by stenoses/occlusions or embolisms from vessels with an inflammatory process. Transcranial Doppler (TCD) ultrasound can provide useful information for diagnosis and monitoring during the active phase of the disease. Cerebral embolic signals can be detected by TCD and have been considered a r...

Abstract The health and productivity of black walnut (Juglans nigra L.) is currently threatened by Thousand Cankers Disease (TCD), a pest complex comprised an insect vector, the twig beetle (WTB) (Pityophthorus juglandis Blackman) (Coleoptera: Curculionidae), associated pathogenic fungi (Geosmithia morbida Kolařík, Freeland, Utley, Tisserat) (Hypocreales: Bionectriaceae). There urgent need for ...

Diante da pandemia COVID-19, muitos professores tiveram que enfrentar a abrupta mudança do ensino presencial para o Ensino Remoto Emergencial (ERE). Logo, utilizaram as Tecnologias de Comunicação Digital (TCD) mediar os processos e aprendizagem. Agora, necessidade formação compreender potencialidade TCD ficou ainda mais evidente e, mesmo com retorno das aulas presenciais ou híbrido, ERE pode in...

BACKGROUND AND PURPOSE Carotid endarterectomy clearly benefits patients with symptomatic severe stenosis (SCS), but the risk of stroke is so low for asymptomatic patients (ACS) that the number needed to treat is very high. We studied transcranial Doppler (TCD) embolus detection as a method for identifying patients at higher risk who would have a lower number needed to treat. METHODS Patients ...

BACKGROUND AND PURPOSE Targeted ultrasound contrast agents have recently been developed to adhere selectively to specific pathogenic materials such as plaque or thrombus. Administration of such microbubbles has potential to aid transcranial Doppler ultrasound (TCD) detection of emboli and to act as markers for distinguishing one embolic material from another. The purpose of this study was to in...

Background: vertigo may be a warning sign of impending vertebrobasilar stroke. Objective: To investigate the role of brain stem auditory evoked potential (BAEP), electronystagmography (ENG) studies and results of transcranial Doppler (TCD) in patients with vertigo of vertebrobasilar origin and patients with vertigo of non-vertebrobasilar origin. Methods: Twenty five patients with vertigo aged 4...

We have engineered a soluble, stable two-chain dimeric streptavidin (TCD) in Escherchia coli. Examination of the three-dimensional structure of streptavidin aided by empirical binding free-energy calculations helped us to select mutations at subunit interfaces that dissociate the native tetramer and stabilize the desired dimer. We chose positions W120, L124, V125 and H127 and mutated them to 12...