نتایج جستجو برای: ssc niche
تعداد نتایج: 26865 فیلتر نتایج به سال:
OBJECTIVE Fetal microchimerism has been hypothesized as a potential pathogenic mechanism for systemic sclerosis (SSc). This hypothesis was based on the clinical similarities between SSc and graft-vs-host disease and the identification of microchimeric cells in affected SSc tissues. The aim of this study was to compare the quantity of microchimeric cells in clinically affected and non-affected s...
INTRODUCTION Esophageal involvement in patients with systemic sclerosis (SSc) is common, but tissue-specific pathological mechanisms are poorly understood. There are no animal scleroderma esophagus models and esophageal smooth muscle cells dedifferentiate in culture prohibiting in vitro studies. Esophageal fibrosis is thought to disrupt smooth muscle function and lead to esophageal dilatation, ...
Traditional measurements of suspended sediment concentrations (SSC) through in-situ sampling in rivers are expensive and time-consuming to perform. Thus, these methods cannot provide continuous SSC records. Although remote sensing has been used for SSC estimation, little research has been undertaken on inland rivers, especially for highly turbid rivers like the Yangtze. Previous studies have pr...
Letter to the Editor: Re: Increased Periodontal Attachment Loss in Patients With Systemic Sclerosis.
BACKGROUND Patients with inflammatory rheumatic diseases and periodontitis share common pathogenetic characteristics, such as proinflammatory traits causative for tissue degradation and loss of function. The aim of the present case control study is to investigate the association between systemic sclerosis (SSc) and periodontitis. METHODS The association between SSc and periodontitis was exami...
OBJECTIVES The patient perspective captured using Patient-Reported Outcome (PRO) instruments provide insight into the patient condition not always captured by physician-derived assessment tools. Target patient population involvement is an essential component of PRO instrument development. We have reviewed the level of patient involvement in the development of PRO instruments used in the assessm...
STUDY OBJECTIVES Obliterative pulmonary vascular disease manifested clinically as pulmonary hypertension (PHT) may complicate systemic sclerosis (SSc). The aim of this study was to investigate possible endothelial dysfunction in patients with SSC complicated by PHT. DESIGN Prospective, randomized trial. SETTING Postgraduate teaching hospital. PATIENTS Patients having SSc with PHT (SSc-PHT...
Objective. Advanced glycation endproducts (AGEs), including Ne-(carboxymethyl)lysine-protein adducts (CML) are involved in micro/macrovascular changes and are co-localized with adhesion molecules in inflamed tissues. Serum levels of CML were investigated in systemic sclerosis (SSc) characterized by microvascular modifications and correlated with indices of micro/ macrovascular damage. Methods. ...
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