Solid Dispersions were prepared by solvent evaporation technique using microcrystalline cellulose, PEG 4000, PEG 6000, PVP-K30 and Gelucire 50/13. Further objective of the project was to develop fast release surface solid dispersion of glibenclamide and compressed at low pressure to form fast-melting pharmaceutical tablet. In this study, we used sodium starch glycolate for mouth dissolving natu...

Octenyl succinic anhydride (OSA) modified starch is widely used in emulsion and encapsulation applications. The functionality of OS starch depends on its molecular structure. A systematic study was performed to investigate the reaction of OSA with granular waxy maize (WM) starch, microporous WM starch and soluble maltodextrin. OS starches were prepared in an aqueous slurry system, and the degre...

Understanding the relationships between biochemical contents and morpho-phenological aspects of a plant during life cycle would be helpful for doing precise agricultural practices through its cultivation. In the present study, various biochemical parameters were evaluated in relation to bulb storage, shoot growth and florogenesis in Iranian lily (Lilium ledebourii var. Kelardasht Salehi1). Ten ...

Altace Tablets (ramipril) are supplied as tablets for oral administration containing 1.25 mg, 2.5 mg, 5 mg and 10 mg of ramipril. The inactive ingredients present are calcium sulphate dihydrate, pregelatinized starch, sodium bicarbonate, and sodium stearyl fumarate. The 2.5 mg tablet contains yellow iron oxide and FD&C yellow #6, the 5 mg tablet contains FD&C yellow #6 and FD&C red #40, and the...

ALTACE Tablets (ramipril) are supplied as tablets for oral administration containing 1.25 mg, 2.5 mg, 5 mg and 10 mg of ramipril. The inactive ingredients present are calcium sulphate dihydrate, pregelatinized starch, sodium bicarbonate, and sodium stearyl fumarate. The 2.5 mg tablet contains yellow iron oxide and FD&C yellow #6, the 5 mg tablet contains FD&C yellow #6 and FD&C red #40, and the...

Amlodipine besylate is a long‐acting calcium channel blocker used to treat chronic stable angina, vasospastic angina and hypertension. Amlodipine is a sparingly soluble orally administered drug and the rate of absorption is often controlled by the rate of dissolution. The rate of dissolution will increase by incorporating the drug in a fast dissolving dosage form. An attempt will be made to dev...

Suitability of various substrates for anaerobic biodegradation of DDT in contaminated soil was tested in lab-scale tests with granular sludge inoculation. Use of carbohydrate-based substances such as starch, sucrose, molasses and whey resulted in acidification, which in extreme cases inhibited DDT removal. A large amount of phosphate buffer prevented pH drop for starch, but not for sucrose. Bet...

The main objective of the research work is to improve the solubility and dissolution rate of olmesartan medoxomil by complexation with HP β-Cyclodextrins. The inclusion complexes were prepared by kneading method and solvent evaporation method. The prepared complexes were characterized by Fourier Transform Infrared Spectroscopy (FTIR) and by scanning electron microscopy (SEM). The FTIR spectra o...

Native sago starch was phosphorylated with 5% sodium tripolyphosphate (STPP) or crosslinked with 4% phosphorous oxychloride (POCl3) at pH 8 to 11. The modified starches were characterized for degree of substitution (DS), pasting properties, crystallinity and molecular structure. The results indicated that DS of phosphorylated sago starch prepared at pH 9 was 0.008, which was the highest value a...

Determination of pasta cooking quality was more dependent on a continuous protein network than the physicochemical properties of gelatinized starch. In the absence of coagulated protein, “starch pasta” strands fractured into small pieces and did not swell in contrast to pasta made from flour or semolina after 20 minutes cooking. The starch of semolina was not a key factor related to better cook...