PURPOSE The practice of intentional rounding up of serum creatinine (SCr) in elderly patients with low measured values can lead to an underestimation of creatinine clearance and subsequent inaccurate dosing of medications. Thus, the purpose of this study was to evaluate the accuracy of vancomycin dose calculations for patients aged ≥65 years using an SCr rounded up to 1 mg/dL versus actual SCr....

Does CyP play a role in HIV-1 replication? CyPA, the member of the CyP family that colocalizes with Gag in College of Physicians and Surgeons 701 West 168th Street the cytoplasm, is specifically incorporated into HIV-1 virions via interaction with the Gag polyprotein Gag binding to CyPA requires a proline-rich region located in the center of the CA domain, and mutation of a single proline, P90,...

BACKGROUND The elevation of serum creatinine (SCr), acute kidney injury (AKI), is associated with an increase of mortality in critically ill patients. However, it is uncertain whether a decrease in SCr in the intensive care unit (ICU) has an effect on outcomes. METHODS In a retrospective study, we enrolled 486 patients who had been admitted to an urban tertiary center ICU between Jan 2014 and...

Skin conductance (SC) data are usually characterized by a sequence of overlapping phasic skin conductance responses (SCRs) overlying a tonic component. The variability of SCR shapes hereby complicates the proper decomposition of SC data. A method is proposed for full decomposition of SC data into tonic and phasic components. A two-compartment diffusion model was found to adequately describe a s...

As a new optical coherence tomography (OCT) imaging modality, there is no standardized quantitative interpretation of OCT angiography (OCTA) characteristics of sickle cell retinopathy (SCR). This study is to demonstrate computer-aided SCR classification using quantitative OCTA features, i.e., blood vessel tortuosity (BVT), blood vessel diameter (BVD), vessel perimeter index (VPI), foveal avascu...

To evaluate regulated gases and solid particle number (SPN) emissions in high-load off-cycle conditions, two diesel vehicles with a particulate filter (DPF) urea selective catalytic reduction (SCR) system, respectively, four gasoline port fuel injection (PFI) were tested the worldwide light-duty test cycle, including an extra-high (Ex-hi) phase. All developed for Japanese market did not comply ...

In 1932, Müller first used the term "antimorphic" to describe mutant alleles that have an effect that is antagonistic to that of the wild-type allele from which they were derived. In a previous characterization of mutant alleles of the Drosophila melanogaster Hox gene, Sex combs reduced (Scr), we identified the missense, antimorphic allele Scr(14), which is a Ser10-to-Leu change in the N-termin...

In this paper, we report our experiments at NTCIR-12 Spoken Query&Doc-2 task. We participated spoken query driven spoken content retrieval (SQ-SCR) subtasks of Spoken Query&Doc2. We submited two types of results, which are conventional spoken content retrieval method (referred to as C-SCR) and STD based approach for SCR (referred to as STD-SCR). The latter was proposed in order to deal with spe...

The results of a study by electron microscopy of the cytopathic effects produced by the San Carlos viruses on cultured human embryo hepatocytes are reported. Examination of liver cells infected with San Carlos virus 6 revealed single virions and crystalline arrays with the hexagonal virion contour measuring an average of 65 to 70 mmu. However, associated with this predominant virion a smaller v...