نتایج جستجو برای: severe acquired aplastic anemia
تعداد نتایج: 541227 فیلتر نتایج به سال:
I N 1961, WE REPORTED 20 cases of severe aplastic anemia in which infusions of allogenic ( homologous ) bone marrow had been used as one of the therapeutic methods.1 Seven of these patients made apparently complete recoveries; whether coincidentally or in rlationship to the marrow infusions is not clear. Since then, the use of allogeneic bone marrow infusions has been wellnigh discarded for the...
I N 1961, WE REPORTED 20 cases of severe aplastic anemia in which infusions of allogenic ( homologous ) bone marrow had been used as one of the therapeutic methods.1 Seven of these patients made apparently complete recoveries; whether coincidentally or in rlationship to the marrow infusions is not clear. Since then, the use of allogeneic bone marrow infusions has been wellnigh discarded for the...
Aplastic anemia, an unusual hematologic disease, is the paradigm of the human bone marrow failure syndromes. Absence of hematopoietic cells has been recognized from the characteristic morphology for a century; an immune pathophysiology has been inferred from improvement in blood counts with immunosuppressive therapy in the majority of patients. Molecular mechanisms underlying both T cell effect...
Eleven of twenty-four patients with severe aplastic anemia given marrow grafts from HLA-identical siblings between October 1970 and March 1973 are alive with normal marrow function and continued evidence of engraftment 3-5 yr later. Ten have been leading normal lives with no immunosuppressive or other drug therapy since day 100 postgrafting. One has had chronic graft-versus-host disease of the ...
1Department of Pediatrics, Hyogo Children Hospital, Hyogo; 2Department of Pediatrics, Nagoya University Graduate School of Medicine, Aichi; 3Department of Pediatrics, Kobe University Graduate School of Medicine, Hyogo; 4Department of Pediatrics, Hokkaido University Graduate School of Medicine, Hokkaido; 5Department of Pediatrics, Yamaguchi University School of Medicine, Yamaguchi; 6Department o...
Emphysematous gastritis is a life-threatening disease. It is characterized by the presence of gas within the wall of the stomach. The etiology includes firstly infections with gas-forming organisms; other predisposing causes are the ingestion of corrosive substances and alcohol abuse. Diagnosis is based on radiological techniques, mainly computed tomographic scan (CT). The election treatment is...
One-way mixed leukocyte cultures were used to study the ability of cells from 53 patients with aplastic anemia and 65 of their HLA-identical siblings to stimulate and to respond to cells from unrelated individuals. The capacity of leukocytes from 28 of 53 patients to stimulate was diminished or absent, wheras their ability to respond remained comparable to that of cells from their HLA-identical...
Acquired aplastic anemia is an idiopathic paradigm of human bone marrow failure syndrome, which involves active destruction of hematopoietic stem cells and progenitors by cytotoxic T cells in the bone marrow. Aberrant expression of microRNAs in T cells has been shown to lead to development of certain autoimmune diseases. In the present study, we performed a microarray analysis of miRNA expressi...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید