Background: Heavy exercise cause muscle damage associated with production of inflammatory agents. The purpose of present study was to determine the effect of acute and 14-day Coenzyme Q10 supplementation on inflammatory, blood lactate and muscle damage in male middle-distance runners.   Methods : Eighteen male middle-distance runners in a randomized and quasi experimental study were allocated...

The objective of this study was to compare and investigate differences in glucose and lactate concentrations in sodium fluoride/potassium oxalate (NaF/Ox) plasma and serum in healthy cats and cats with metabolic disease. Glucose and lactate concentrations were determined in routinely processed serum and NaF/Ox plasma obtained from healthy (n=30), hyperthyroid (n=27) and diabetic (n=30) cats, an...

OBJECTIVES To demonstrate that small intestinal mucosal ischemia occurs during cardiopulmonary bypass by measuring serum diamine oxidase activity, an index of small intestinal mucosal ischemia, in perioerative patients undergoing cardiovascular surgery with and without cardiopulmonary bypass. METHODS Twelve successive patients who underwent coronary artery bypass grafting with cardiopulmonary...

The objective of this research was to evaluation metabolic, biochemical and hematological parameters in dairy cattle with displacement the abomasum (DA). In study, 80 DA 10 healthy early lactation were used. Jugular venous blood samples for gases, serum analysis all taken. Glucose, lactate, triglycerides, BHB, NEFA, insulin, VLDL, GGT, CK concentrations pH hematocrit value significantly (P

Increased cerebral lactate levels are a well-known aspect of the sequelae of the metabolic derangements that follow cerebral ischemia. A new technique has recently become available to sample cerebral venous blood from the superior sagittal sinus on a long-term basis in conscious rats. We report the applicability of this method to assess serial biochemical responses to brain injury. Serum sample...

1. Statins inhibit synthesis of mevalonate, a precursor of ubiquinone that is a central compound of the mitochondrial respiratory chain. The main adverse effect of statins is a toxic myopathy possibly related to mitochondrial dysfunction. 2. This study was designed to evaluate the effect of lipid-lowering drugs on ubiquinone (coenzyme Q10) serum level and on mitochondrial function assessed by b...

PURPOSE The diagnostic classification of disorders of consciousness is often challenging, particularly the distinction between epileptic and non-epileptic seizures. The aim of the study was to examine serum lactate as a diagnostic marker of transient loss of consciousness. METHOD Serum lactate levels in blood samples drawn within 2h of the event were compared retrospectively between patients ...

1. Circulating concentrations of intermediary metabolites have been measured after administration of 50 mg of phenformin to normal subjects. 2. Phenformin caused a significant increase in blood lactate, alanine and the lactate/pyruvate ratio but did not affect blood glucose or serum insulin concentrations. 3. There was a significant correlation between the increase in blood lactate concentratio...

Lactic acid (2-Hydroxypropanoic acid) or lactate (ionic form of lactic acid) is generated from pyruvic acid under anaerobic condition in all tissues like skeletal muscle, brain, RBC and kidney. The normal level of lactic acid in serum is in the range of 0.5-2.2 mM. During exercise and extensive work, its level in blood increases upto 12 mM and 25 mM. Lactate level is measured in dairy products ...