cyclotides are small disulfide-rich proteins that have the unusual feature of a cyclic backbone. cyclotides have a range of interesting biological activities and are found in a variety of tropical plants from the rubiaceae, violaceae, cucurbitaceae and fabaceae families. we have cloned and characterized cyclotides in viola modesta, a viola species native to western asia, which was collected fro...

Local feature methods suitable for image feature based object recognition and for the estimation of motion and structure are composed of two steps, namely the ‘where’ and ‘what’ steps. The ‘where’ step (e.g., interest point detector) must select image points that are robustly localizable under common image deformations and whose neighborhoods are relatively informative. The ‘what’ step (e.g., l...

introduction: asymptomatic diabetic patients are at increased risk of cardiovascular complications. myocardial perfusion scan may be effective in risk evaluation in this population. methods: 106 asymptomatic diabetic patients (age: min: 37, max: 82, mean: 57.73±8.88), including 56 females (52.8%) and 50 males (47.2%) were enrolled in the study. myocardial perfusion scintigraphy was performed by...

1. Repeating bursts of motor neurone impulses have been recorded from the nerves of completely isolated nerve cords of the medicinal leech. The salient features of this burst rhythm are similar to those obtained in the semi-intact preparation during swimming. Hence the basic swimming rhythm is generated by a central oscillator. 2. Quantitative comparisons between the impulse patterns obtained f...

In this paper we investigate an application of feature clustering for word sense disambiguation, and propose a semisupervised feature clustering algorithm. Compared with other feature clustering methods (ex. supervised feature clustering), it can infer the distribution of class labels over (unseen) features unavailable in training data (labeled data) by the use of the distribution of class labe...

A quantitative structure activity relationship analysis was applied to a library of 51 benzylacetamide derivatives with anticonvulsant activity. The molecular structures of 51 compounds were optimized with the Semiempirical Method PM6 (Parametric Method-6) included in the MOPAC2009 software. The optimized structures of all the examined compounds were represented by 1497 DRAGON-type descriptors....

Explosive growth of multimedia data has brought challenge of how to efficiently browse, retrieve and organize these data. Under this circumstance, different approaches have been proposed to facilitate multimedia analysis. Several semi-supervised feature selection algorithms have been proposed to exploit both labeled and unlabeled data. However, they are implemented based on graphs, such that th...

For the non-cardiologist emergency physician and intensivist, performing an accurate estimation of left ventricular ejection fraction (LVEF) is essential for the management of critically ill patients, such as patients presenting with shock, severe respiratory distress or chest pain. Our objective was to develop a semi-quantitative method to improve visual LVEF evaluation. A group of 12 sets of ...

The conceptually simple step from cross-linking/mass spectrometry (CLMS) to quantitative cross-linking/mass spectrometry (QCLMS) is compounded by technical challenges. Currently, quantitative proteomics software is tightly integrated with the protein identification workflow. This prevents automatically quantifying other m/z features in a targeted manner including those associated with cross-lin...