In March 2010, the U.S. Fish and Wildlife Service (FWS) identified the greater sage-grouse (Centrocercus urophasianus; sage-grouse) as a candidate species for protection under the Endangered Species Act (ESA) because of habitat loss and fragmentation and that regulatory mechanisms needed to protect the species and its habitat were inadequate. However, after further review of on-going range wide...

Sagebrush (Artemisia spp.) habitats being developed for oil and gas reserves are inhabited by sagebrush obligate species-including the greater sage-grouse (Centrocercus urophasianus; sage-grouse) that is currently being considered for protection under the U.S. Endangered Species Act. Numerous studies suggest increasing oil and gas development may exacerbate species extinction risks. Therefore, ...

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada. Institute for Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada. Department of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario M5S 3G4, Canada. Division of Thoracic Surgery, University of Toron...

The Greater sage-grouse (Centrocercus urophasianus) occupies the sage brush habitats of Western North America. Large population declines in the last several decades have made it a candidate for possible listing under the Endangered Species Act. Listing was recently avoided in part because seventy local working groups are developing long-range management plans in conjunction with federal and loc...

The SAGE (Standards-Based Active Guideline Environment) project was formed to create a methodology and infrastructure required to demonstrate integration of decision-support technology for guideline-based care in commercial clinical information systems. This paper describes the development and innovative features of the SAGE Guideline Model and reports our experience encoding four guidelines. I...

I f the achievement of complete sequencing of the one-dimensional genetic codes of the human genome can be compared with man landing on the moon, the interpretation of genomic instruction in a four-dimensional biological context, such as during development and diseases, will prove to be a much more challenging and daunting task than that of getting man back from the moon to the earth. One of th...

This paper describes a new sampling-based heuristic for tree search named SAGE and presents an analysis of its performance on the problem of grammar induction. This last work has been inspired by the Abbadingo DFA learning competition [14] which took place between Mars and November 1997. SAGE ended up as one of the two winners in that competition. The second winning algorithm, rst proposed by R...

It has been 7 years since serial analysis of gene expression (SAGE) and microarray hybridization techniques were simultaneously introduced to allow the screening of thousands of expressed genes. Both techniques have stood up to the test of time as evidenced by their widespread use, and both have been used for studying cardiovascular diseases. SAGE has been used more extensively to study cancer ...

iii Acknowledgments iv Chapter 1. A Hierarchy of Polyhedral Arrangements 1 1.1. Polyhedral Arrangements 1 1.2. Polyhedral Dissections 1 1.3. Polyhedral Complexes 5 1.4. Polyhedral Triangulations 8 1.5. A Hierarchy of Polyhedral Arrangements 9 Chapter 2. Computation on Polyhedral Arrangements 12 2.1. Bucket Method 12 2.2. Sage Code 13 2.3. Experiments 16 Chapter 3. Regular Triangulations 22 3.1....

The Serial Analysis of Gene Expression (SAGE) method, described in 1995 by Velculescu et al ., represents a powerful means to compare gene expression between two mRNA populations. An improvement to SAGE that removes contaminating linker molecules, which compromise the efficiency of the method, has been developed. This modification utilises biotinylated PCR primers, which generate biotinylated l...