Background: Fatigue is one of the most prevalent and debilitating complications of cancer and its treatments. Patients with radiotherapy experience some degrees of fatigue. Complementary medicine methods, have reduced the complications of treatments in many disorders. Accordingly, the present study was conducted with the aim of comparing the effect of aromatherapy by inhalation and massage on R...

musa sapientum (m.sapientum) commonly known as ‘banana’ is widely used in bangladeshi folk medicine for the treatment of various ailments including diarrhea. hence, the present study was designed to investigate antidiarrheal, antioxidant and antibacterial potential of the methanolic extract of m.sapientum seed (mmss). the extract was studied for antidiarrheal property using castor oil and magne...

Irinotecan (Camptosar) is an active chemotherapeutic agent for lung, gastric, esophageal, and colorectal cancers and a potent radiosensitizer. This phase I study was designed to assess the maximum tolerated dose of weekly irinotecan combined with concurrent radiotherapy for patients with locally advanced, unresectable gastric, gastroesophageal junction, or esophageal cancer. Patients who receiv...

PURPOSE We compared dosimetry and clinical toxicity for 3-dimensional conformal radiotherapy (3D-crt), intensity-modulated radiotherapy (imrt), and RapidArc (Varian Medical Systems, Palo Alto, CA, U.S.A.) in locally advanced pancreatic cancer (lapcc). We hypothesized that the technique with better sparing of organs at risk (oars) and better target dose distributions could lead to decreased clin...

background and aims. xerostomia is one of the most common complications of head and neck radiotherapy. the aim of this study was to evaluate and compare the efficacy of pilocarpine and bromhexine in improving radiotherapy-induced xerostomia and its associated symptoms. materials and methods. in this single-blind, randomized crossover study, pilocarpine and bromhexine tablets were used by twenty...

introduction: while the development of fistulae is a well-known complication of radiotherapy, such fistulae can often be challenging to manage. case presentation: we describe the case of a 37 year old male who developed in succession a urethrocutaneous fistula to the thigh, a rectourethral fistula and a peritoneo-urethral fistula 35 years after radiotherapy for pediatric pelvic rhabdomyosarcoma...

BACKGROUND Over 80% of head and neck cancer patients suffer from radiotherapy-induced xerostomia (dry mouth). Xerostomia affects cancer patients' quality of life, and xerostomia sometimes persists throughout the patients' lifetime. This review aimed to evaluate the effectiveness and safety of Chinese herbs in relieving radiotherapy induced xerostomia. METHODS Systematic searches were conducte...

Morphoea is a chronic inflammatory disease of the skin and underlying tissues, characterised by fibrosis subcutaneous tissue without systemic involvement. Radiation-induced morphoea rare, often unrecognised, chronically progressive form radiation-associated localised scleroderma skin, infrequently progressing to scleroderma. Systemic widespread along with features, leading an increased risk mal...

BACKGROUND & AIMS Diseases of the human gastrointestinal (GI) tract are often accompanied by diarrhea with profound alterations in the GI microbiota termed dysbiosis. Whether dysbiosis is due to the disease itself or to the accompanying diarrhea remains elusive. With this study we characterized the net effects of osmotic diarrhea on the composition of the GI microbiota in the absence of disease...

AIM To clarify the roles of TWEAK and its receptor Fn14 in 5-fluorouracil (5-FU)-induced diarrhea. METHODS Diarrhea was induced in wild-type (WT), Fn14 knockout (KO), and IL-13 receptor (IL-13R)α1 KO BALB/c mice using a single injection of 5-FU. Histological analysis, cytokine analysis, and flow cytometry was performed on ileal tissues and cells. Murine colon carcinoma-bearing mice were co-tr...