. 12.00 background: prenatal care is a comprehensive antepartum care program involving a coordinated approach to medical care and psychosocial support that is optimally offered before conception. inadequate care during pregnancy can lead to undesirable outcomes, including preterm labor and low birth weight. one of these new, accurate, and comprehensive indicator measurements is adequacy of pren...

OBJECTIVE Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this stud...

Preterm birth is a significant problem occurring in around 10% of all deliveries and its increase is remarkable, even in developed countries. Being born under 37 weeks, and most importantly under 32 weeks, is the major cause of perinatal morbidity and mortality and accounts for the majority of neonatal deaths. Recent advances in perinatology and neonatology have increased survival rates, partic...

OBJECTIVE The purpose of this study was to evaluate the effectiveness of antibiotic treatment of bacterial vaginosis in pregnancy to reduce preterm delivery. STUDY DESIGN We performed a meta-analysis of published, English-language, randomized, placebo-controlled clinical trials of antibiotic treatment of bacterial vaginosis in pregnant women with intact amniotic membranes at <37 weeks of gest...

Background and objective: Several studies have been conducted about Bacterial Vaginosis and its relation with preterm labor that was accompanied with controversial results. The aim of this study was to compare the frequency of Bacterial Vaginosis and common genitourinary infections between term and pre-term pregnancies. Methods: In a case-control study, 249 pregnant women admitted to Shohadyae ...

The present study tested the hypothesis that ERK activation is an essential step in the onset of labor in a rat model of preterm labor. The administration of RU-486, an antiprogesterone agent, to rats induced preterm delivery 22.2 +/- 0.24 h after treatment. Changes in basal signaling events were studied in myometrial tissue from CO(2)-euthanized rats. Rats treated with RU-486 displayed a drama...

The present study tested the hypothesis that ERK activation is an essential step in the onset of labor in a rat model of preterm labor. The administration of RU486, an antiprogesterone agent, to rats induced preterm delivery 22.2±0.24 hrs after treatment. Changes in basal signaling events were studied in myometrial tissue taken from CO2 euthanized rats. Rats treated with RU486 displayed a drama...

Introduction. In Netherlands, the obstetric care system is divided into primary and secondary care by risk level of the pregnancy. We assessed the incidence of preterm birth according to level of care and the association between level of care at time of labor onset and delivery and adverse perinatal outcome. Methods. Singleton pregnancies recorded in Netherlands Perinatal Registry between 1999 ...

BACKGROUND Although several socio-medical risk factors have been identified for preterm labor, there is a gap in understanding the underlying etiology of preterm labor. OBJECTIVES The current study aimed to analyze the relationship pathway of perceived social support, stressful life events, and other psychosocial risk factors during pregnancy with incidence of preterm labor. MATERIALS AND M...

According to the World Health Organization (WHO) recommendation,[1] preterm labor is defined as labor starting earlier than 37 completed weeks (less than 259 days) from the first day of the last menstrual period and the term premature should no longer be used. The term premature was previously defined as a birth weight of less than 2500 gm. Therefore, this will include infants of low birth weig...