نتایج جستجو برای: photosensitizer
تعداد نتایج: 2488 فیلتر نتایج به سال:
An optical fiber has been developed with a maneuverable mini-probe tip that sparges O(2) gas and photodetaches pheophorbide (sensitizer) molecules. Singlet oxygen is produced at the probe tip surface which reacts with an alkene spacer group releasing sensitizer upon fragmentation of a dioxetane intermediate. Optimal sensitizer photorelease occurred when the probe tip was loaded with 60 nmol sen...
Synergistic therapy is a promising strategy for cancer treatment. A nanoparticle with chemo-photodynamic properties was fabricated via π-π stacking interactions between the drug and photosensitizer. It exhibited efficient anticancer activity both in vitro and in vivo.
The aim of this study was to assess the anti-tumor effect of photodynamic therapy (PDT) using a novel bacteriochlorophyll derivative, palladium-bacteriopheophorbide (TOOKAD) on tumor growth, perfusion and oxygenation. Rat DS-sarcomas were treated with either TOOKAD-PDT (2 mg/kg, i.v., immediate illumination) or one of the control treatments (sham-treatment, illumination without photosensitizer,...
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