نتایج جستجو برای: photosensitizer

تعداد نتایج: 2488  

Journal: :Journal of the American Chemical Society 2011
Matibur Zamadar Goutam Ghosh Adaickapillai Mahendran Mihaela Minnis Bonnie I Kruft Ashwini Ghogare David Aebisher Alexander Greer

An optical fiber has been developed with a maneuverable mini-probe tip that sparges O(2) gas and photodetaches pheophorbide (sensitizer) molecules. Singlet oxygen is produced at the probe tip surface which reacts with an alkene spacer group releasing sensitizer upon fragmentation of a dioxetane intermediate. Optimal sensitizer photorelease occurred when the probe tip was loaded with 60 nmol sen...

Journal: :Journal of the American Chemical Society 2011

Journal: :Chemical communications 2015
Xin Deng Yan Liang Xinyu Peng Ting Su Song Luo Jun Cao Zhongwei Gu Bin He

Synergistic therapy is a promising strategy for cancer treatment. A nanoparticle with chemo-photodynamic properties was fabricated via π-π stacking interactions between the drug and photosensitizer. It exhibited efficient anticancer activity both in vitro and in vivo.

Journal: :THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE 1988

Journal: :International journal of oncology 2004
Debra K Kelleher Oliver Thews Avigdor Scherz Yoram Salomon Peter Vaupel

The aim of this study was to assess the anti-tumor effect of photodynamic therapy (PDT) using a novel bacteriochlorophyll derivative, palladium-bacteriopheophorbide (TOOKAD) on tumor growth, perfusion and oxygenation. Rat DS-sarcomas were treated with either TOOKAD-PDT (2 mg/kg, i.v., immediate illumination) or one of the control treatments (sham-treatment, illumination without photosensitizer,...

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