Organophosphorus hydrolase can effectively degrade organic phosphorus compounds such as sarin. In this study, we constructed a recombinant Bacillus subtilis mutant expressing organophosphorus hydrolase, measured the effect of on degradation rate nerve agent sarin, and selected optimal mutation scheme. Three different genes, 257L, 257Y 303T, were ligated to PMA0911 vector transferred into WB800 ...

Organophosphorus Compound Poisoning is one of the most common toxicological emergencies encountered particularly in rural agricultural patients presenting to emergency department Hitech Medical College and Hospital Bhubaneswar, Odisha. Atotal 372 cases organophosphorus compound poisoning were analyzed during three-year period from January 2017 December 2020. The basic demographic data such as a...

Fatty acid amide hydrolase (FAAH) plays an important role in nerve function by regulating the action of endocannabinoids (e.g., anandamide) and hydrolyzing a sleep-inducing factor (oleamide). Several organophosphorus pesticides and related compounds are shown in this study to be more potent in vivo inhibitors of mouse brain FAAH than neuropathy target esterase (NTE), raising the question of the...

Resistance to organophosphorus, carbamate and pyrethroid insecticides in the diamondback moth, Plutella xylostella (L.) is widespread in Japan. Consequently, tertiary amines such as cartap and thiocyclam, microbial insecticides (formulations of Bacillus thuringiensis Berliner) and chitin synthesis inhibitors have been widely used for control. A high level of resistance to these alternative inse...

OBJECTIVE The purpose of this work was to compare DNA damage, acetylcholinesterase (AChE) activity, inflammatory markers and clinical symptoms in farmers exposed to organophosphorus pesticides to individuals that had no pesticide exposure. MATERIALS AND METHODS We conducted a cross-sectional survey with a total of 134 people. The subject group consisted of 67 farmers who were exposed to organ...

High levels of resistance to the major categories of insecticides, ie, organophosphorus, carbamates, pyrethroids, and DDT, have been detected in the diamondback moth in Taiwan. Synergist studies have provided insufficient evidence to show significant involvement of known metabolic systems, such as microsomal oxidation, esterase hydrolysis, and glutathione conjugation in organophosphorus and car...

Andersen, K. F., Morris, L., Derksen, R. C., Madden, L. V., and Paul, P. A. 2014. Rainfastness of prothioconazole + tebuconazole for Fusarium head blight and deoxynivalenol management in soft red winter wheat. Plant Dis. 98:1398-1406. Fungicides are most warranted for control of Fusarium head blight (FHB), a disease of wheat caused by the fungal pathogen Fusarium graminearum, when wet, rainy co...

Objective The extensive pollution of natural ecosystems has occurred by organophosphorus pesticides, being used for improvement of crop production in agriculture. Biodegradation is interested in application of multifunctional bacteria containing genetical elements which specially degrade organophosphorus compounds. In this paper the detection of two bacteria species, Pseudomonas and Flavobacte...