OBJECTIVES Oral submucous fibrosis (OSMF) is a potentially malignant disorder of oral cavity, pharynx and upper digestive tract, characterized by progressive inability to open the mouth. Based on clinical and/or histopathological features, various classifications and grading systems have been put forth till date. The aim of the present study was to study the variance in cheek flexibility in OSM...

BACKGROUND Oral submucous fibrosis (OSF) is an insidious chronic condition characterized by restricted mouth opening. Prosthetic rehabilitation is challenging for OSF patients as obtaining a good impression requires adequate mouth opening. The aim of the present review is to systematically present the data from case reports published in the English-language literature. METHOD A comprehensive ...

BACKGROUND Oral submucous fibrosis (OSF) is a common oral health problem in the Indian subcontinent. It is characterized by a juxtaepithelial inflammatory reaction followed by fibroelastic changes in the lamina propria. Traditionally, it is said to be associated with marked epidermal atrophy and decreased vasculature as the disease advances. OBJECTIVE To assess the changes in epidermal thickn...

Oral sub mucous fibrosis is a crippling disease of mouth with high malignant potential that has high prevalence rate in India and South East Asia. The treatment of patients with oral submucous fibrosis depends on the degree of clinical involvement. If the disease is detected at a very early stage, cessation of the habit is sufficient. Medical treatment is symptomatic and predominantly aimed at ...

Context: Oral squamous cell carcinomas develop from a premalignant lesion or condition, which are due to a variety of aetiological factors. Early detection of these are necessary to prevent them from developing into carcinomas which can increase the mortality and morbidity. There are a variety of possible aids like histopathology, Hstiochemistry and Enzyme assays in diagnosing these lesions. Hi...

BACKGROUND Oral submucous fibrosis (OSF), a potentially malignant oral lesion, is a form of pathological fibrosis affecting the oral mucosa. It results from an imbalance in equilibrium of the normal process of synthesis and degradation of extra cellular matrix. Matrix metalloproteinases and its inhibitors play important role in remodeling of the extra cellular matrix which are important in prog...