The present pre- and postnatal study was carried out to investigate the effect of melatonin (MEL), a potent antioxidant, on biochemical variables in the in vivo model of intrauterine hypoxia in rats. Chronic hypoxia was induced pharmacologically by the administration of the anticonvulsant phenytoin (PHT) during pregnancy. Rats were orally treated by PHT (150 mg/kg) from day 7 to 18 of gestation...

To investigate the relationship between development of obesity and the small intestinal functions two experimental models of male Wistar rats were used in the present work: 1) early postnatally overfed rats, nursed from birth to weaning in small litters (SL, 4 pups/nest), and 2) neonatally monosodium glutamate treated rats (MSG 2 mg/g b.w. administered s.c. for 4 days after birth) submitted to ...

Tyrosinemia type II is a rare autosomal recessive disorder wich can present itself with recurrent epithelial keratitis, hyperkeratotic skin lesions and mental retardation. This article reports the rare occurrence of this disease in both offsprings (two brothers) of a family (consanguinous'marriage) who were managed with a lowprotein diet and a special regimen.

BACKGROUND Autism is a neurodevelopmental disorder with a high estimated heritability. ATP2B2, located on human chromosome 3p25.3, encodes the plasma membrane calcium-transporting ATPase 2 which extrudes Ca(2+) from cytosol into extracellular space. Recent studies reported association between ATP2B2 and autism in samples from Autism Genetic Resource Exchange (AGRE) and Italy. In this study, we ...

The evolution scheme phase, in which the genetic algorithms select individuals that will form new population, had an important impact on these algorithms. Many approaches exist literature. However, consider only value of fitness function to differenciate best solutions from worst ones. This article introduces parenting fitness, a novel parameter, defines capacity individual produce fittest offs...

the influence of parasitoids on population dynamics is affected by host instar preference. the preference pattern of host instars is not fixed and is modified by the availability and relative abundance of host instars, intensity of defensive behaviors in a particular instar, and also maternal effects of the female forager. in this study, host instar preference of the thelytokous strain of lysip...

A Genetic algorithm is a heuristic approach which applies analogies from nature to tackle complex optimization problems. Existing solutions (the ancestors) are randomly modified to produce offsprings which might replace their parents. We apply a genetic algorithm to a special case of a 2D bin packing problem, using a permutation-style representation decoded by a modified first-fit heuristic

Introduction: Cannabis consumption during pregnancy may affect fetal growth, motor performance, memory and cognitive functions. Methods: Primiparous pregnant Wistar rats were randomly assigned to 4 treatment groups (6 rats per group) consisting of control and sham groups as well as 2 groups treated with Win. Win treated groups received daily s.c. injections of 0.5 or 1 mg/kg WIN suspended in 1%...