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The objective of this article is to identify common and atypical features of systemic lupus erythematosus diagnosed following hepatitis B vaccination. We analyzed retrospectively the medical records of 10 systemic lupus erythematosus patients from different centers, who developed the disease following hepatitis B vaccination and determined the prevalence of different manifestations and the time...

Systemic lupus erythematosus (SLE) is an episodic, potentially fatal, multisystem autoimmune disease characterized by the presence of antinuclear antibodies especially to double stranded DNA. Bullous systemic lupus erythematosus is an extremely rare subset of lupus erythematosus. We report a 10-year-old boy with bullous SLE and nephrotic syndrome.

Bullous systemic lupus erythematosus has rarely been described in pediatric lupus population and the real prevalence of childhood-onset bullous systemic lupus erythematosus has not been reported. From January 1983 to November 2013, 303 childhood-onset SLE (c-SLE) patients were followed at the Pediatric Rheumatology Unit of the Childreńs Institute of Hospital das Clínicas da Faculdade de Medicin...

In a disease with such widespread and variable manifestations as systemic lupus erythematosus the diagnosis, at least in the early stages, often depends upon a clinical suspicion supported by laboratory investigations, notably the demonstration of lupus erythematosus (L.E.) cells. While this test is highly specific for systemic lupus erythematosus it has these disadvantages. In a few patients L...

LET: lupus erythematosus tumidus SLE: systemic lupus erythematosus INTRODUCTION Lupus erythematosus tumidus (LET) is a nonscarring form of cutaneous lupus erythematosus that typically presents in middle-age men as urticariallike lesions on sun-exposed areas. There is a paucity of information on black patients with LET. To our knowledge, this case marks the fourth published report of LET in a bl...

UNLABELLED INTRODUCTION The occurrence of systemic lupus erythematosus has been only rarely reported in patients with sickle-cell disease. CASE PRESENTATION We describe the case of a 23-year-old North-African woman with sickle-cell disease and systemic lupus erythematosus, and discuss the pointers to the diagnosis of this combination of conditions and also present a review of literature. T...

BACKGROUND Subacute cutaneous lupus erythematosus is a nonscarring, non-atrophy-producing photosensitive cutaneous disorder. Half of the patients have 4 or more of the criteria for classification as systemic lupus erythematosus. In some patients, drugs induce or exacerbate the cutaneous disease. OBSERVATION We describe 5 patients who had either an exacerbation or a new onset of subacute cutan...

INTRODUCTION Systemic lupus erythematosus is a multi-system connective tissue disorder. Peripheral neuropathy is a known and underestimated complication in systemic lupus erythematosus. Ganglionopathy manifests when neuronal cell bodies in the dorsal root ganglion are involved. Autoimmune disorders are a known etiology, with systemic lupus erythematosus being a rare cause. CASE PRESENTATION A...

Chilblain lupus erythematosus is a rare form of cutaneous lupus erythematosus characterized by bluish red infiltrates in acral locations of the body mostly affecting middle-aged women. We recently described a familial form of chilblain lupus manifesting in early childhood caused by a heterozygous mutation in the TREX1 gene, which encodes a 3'-5' DNA exonuclease. Thus, familial chilblain lupus r...