نتایج جستجو برای: multi drug resistance gene
تعداد نتایج: 2346331 فیلتر نتایج به سال:
UNLABELLED The expression of resistance genes can cause the ineffectiveness of chemotherapeutics for the treatment of cancer. Therefore, known resistance genes were investigated in oral squamous cell carcinoma (OSCC) and the results were compared with clinico-pathological findings. MATERIALS AND METHODS Fresh frozen samples of 45 primary OSCC were investigated for the expression of mdr1 (p-gl...
P-Glycoprotelns represent a family of drug efflux proteins that convey multidrug resistance to cells In which they are expressed. This phenome non can lower the efficacy of drugs used in chemotherapy. The steroid progesterone has been shown to bind P-glycoproteins and inhibit their drug emux. We report that the antiprogestin RU 486 can reverse multi drug resistance In cells overexpressing the m...
Abstract Background and Objective: Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen involved in nosocomial infections. Because of increasing antibiotic resistance of these strains, treatment of these infections has become very difficult. This study aimed to determine the frequency and drug resistance pattern of MRSA isolates from nosocomial infections in hospi...
The emergence of compensatory mutations in the polymerase gene of drug resistant hepatitis B virus (HBV) is associated with treatment failure. We previously identified a multi-drug resistant HBV mutant, which displayed resistance towards lamivudine (LMV), clevudine (CLV), and entecavir (ETV), along with a strong replication capacity. The aim of this study was to identify the previously unknown ...
Salmonella enterica bacteria have become increasingly resistant to antimicrobial agents, partly as a result of genes carried on integrons. Clonal expansion and horizontal gene transfer may contribute to the spread of antimicrobial drug-resistance integrons in these organisms. We investigated this resistance and integron carriage among 90 isolates with the ACSSuT phenotype (resistance to ampicil...
Introduction: Antibiotic resistance in Pseudomonas aeruginosa has become a worldwide problem, and is leading to multi-drug resistance (MDR: Multiple drug resistance). Therefore, this study aimed to determine the antibiotic strain patterns of Pseudomonas aeruginosa isolated from various clinical specimens of patients in hospitals in Yazd. Methods: In this descriptive cross- sectional study, 90...
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