The aim of this study was to investigate the interaction of Candida tropicalis with three different human cell lines: TCC-SUP (epithelial cells from urinary bladder), HeLa (epithelial cells from cervical carcinoma) and Caco-2 (epithelial cells from colorectal adenocarcinoma). In particular we sought to assess the degree of cell damage and activity reduction induced by C. tropicalis adhesion and...

BACKGROUND Multiple sclerosis (MS) is an autoimmune disease of central nerves system, in which neurological disabilities occur in young adults. Despite increasing number of studies on MS, some aspects of this disorder are still unclear. In the previous studies, it has been proven that there is direct relation between MS incidence and vitamin D deficiency. Thereby, strong evidence in MS pathogen...

Proliferative vitreoretinopathy (PVR) is one of the most common causes for failed retinal detachment surgeries. The aim of the present study was to investigate the role of insulin-like growth factor-binding protein-6 (IGFBP-6) in PVR using rat models and its effects on retinal pigment epithelial-J (RPE-J) cells. PVR Wistar rat models were administered intravitreal injection of RPE-J cells (1x10...

PURPOSE Estradiol (E2) modulates testicular functions including steroidogenesis, but the mechanisms of E2 signaling in human testis are poorly understood. GPER-1 (GPR30), a G protein-coupled membrane receptor, mediates rapid genomic and non-genomic response to estrogens. The aim of this study was to evaluate GPER-1 expression in the testis, and its role in estradiol dependent regulation of ster...

Parthenolide (PTL) shows potent anti-inflammatory and anti-cancer activities. In the present study, the molecular mechanisms of PTL's activities were explored in lipopolysaccharide (LPS)-induced human leukemia monocytic THP-1 cells and human primary monocytes. The 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium salt (MTS) assay was used to analyze the ef...

INTRODUCTION We have previously found an increased mast cell density in tendon biopsies from patients with patellar tendinopathy compared to controls. This study examined the influence of mast cells on basic tenocyte functions, including production of the inflammatory mediator prostaglandin E2 (PGE2), extracellular matrix remodeling and matrix metalloproteinase (MMP) gene transcription, and col...

BACKGROUND Gamma-tocotrienol (GTT), an isomer of vitamin E and hydroxy-chavicol (HC), a major bioactive compound in Piper betle, has been reported to possess anti-carcinogenic properties by modulating different cellular signaling events. One possible strategy to overcome multi-drug resistance and high toxic doses of treatment is by applying combinational therapy especially using natural bioacti...

Summtiizary. Primary roots of solution--grown, 5-day-old or 6-day-old seedlings of corn (Zea mays L.) 10 to 14 cm in length were used to study radial salt trtansport. Measurements were made of the volume of root pressure exudation, salt concentration of the exudate, and rate of salt movement into the xylem exudate. The 32p uptake, 09 consumption, and dehydrogenase activity of the root cortex an...

Description Charged MTS reagents Positively charged reagent that reacts very rapidly and specifically with cysteine groups. Useful tools for protein (transporters, receptors...) structure and activity studies These reagents would fit inside a cylinder about 0.6nm in diameter and 1nm in length (Akabas . MTSEA UP996180 100mg 500mg 1g 2-Aminoethyl MethaneThioSulfonate Hydrobromide CAS [16599-33-0]...

In the current study, we fabricated a cardiac patch composed of gold nanowires incorporated in collagen fibres by electrospinning followed chemical crosslinking. Two other counterparts were fabricated; one with without cross linking and only fibres. The surface morphology was viewed via microscopy images complete analysis mechanical strength done. Swelling suture resistance tests along cytotoxi...