Epidemiological studies suggest the existence of close but complex relationships between estrogens, migraine, and stroke in women before menopause. Migraine, particularly without aura, is strongly influenced by estrogens as illustrated by the frequency of onset at puberty, of menstrual migraine, and of improvement during pregnancy. Migraine, particularly with aura, is a risk factor for ischemic...

OBJECTIVE It is uncertain whether migraine prevalence has increased in modern society. The aim of this study was to assess any change in migraine prevalence over an 8-year period among the adult population in Denmark. DESIGN Prospective longitudinal population-based study. SETTING 30 000 twin individuals were invited to participate in two cross-sectional questionnaire surveys containing val...

epilepsy is one of the most common neurological disorders which a physician might come across in his career life. on the other hand, migraine is common disorders in society chronic headache such as migraine in epileptic patients give ride to difficulties in seizure treatment due to altering the sleeping pattern and calmness disarrangement. therefore, early diagnosis and suitable treatment in ep...

Migraine has been associated with sleep disturbances. Relationship between sleep quality and migraine frequency is yet to be determined. The present study aimed to investigate sleep disturbances among low-frequency, moderate-frequency, high-frequency, and chronic migraineurs, with and without auras, with well-controlled confounding variables.This cross-sectional controlled study included 357 su...

BACKGROUND AND PURPOSE Transcatheter closure of patent foramen ovale (PFO) has been reported to improve migraine in patients with cerebrovascular disorders in noncontrolled studies. The aim of the study was to compare the course of migraine assessed prospectively over a 12-month period in symptomatic (for cerebrovascular disease) and asymptomatic patients undergoing PFO closure and in patients ...

Latent class and genetic analyses were used to identify subgroups of migraine sufferers in a community sample of 6,265 Australian twins (55% female) aged 25-36 who had completed an interview based on International Headache Society (IHS) criteria. Consistent with prevalence rates from other population-based studies, 703 (20%) female and 250 (9%) male twins satisfied the IHS criteria for migraine...

background: menstrual migraine (mm) is a subgroup of migraine headache that affect the quality of life of patients in menstrual age. iron deficiency anemia (ida) is the most common cause of anemia, especially in women of reproductive age. objectives: to determine the association of iron deficiency anemia with menstrual migraine. materials and methods: this descriptive-analytic study was conduct...

Migraine is amongst the oldest of diseases known to mankind. Migraine is a heterogenous entity, usually characterised by periodic attacks of headache on one or both sides of the head. These may be accompanied by nausea, vomiting, increased sensitivity of the eyes to light (photophobia), increased sensitivity to sound (phonophobia), dizziness, blurred vision, cognitive disturbances, and other sy...

In this edition of Cephalalgia, Dr Holland and colleagues report the very interesting findings from a series of in vivo cat and rodent experiments aimed at identifying potential therapeutic targets for the modulation of cortical spreading depression (CSD). Over the past two decades, a series of functional neuroimaging studies performed in human migraineurs during acute aura (1–4) have linked CS...

Migraine with aura (MA) is characterized by cortical dysfunction. Frequent aura attacks may alter cerebral cortical structure in patients, or structural grey matter abnormalities may predispose MA patients to aura attacks. In the present study we aimed to investigate cerebral grey matter structure in a large group of MA patients with and without sensory aura (i.e. gradually developing, transien...