In this study, we evaluated the clinical diagnostic value of vestibular evoked myogenic potentials (VEMPs) for endolymphatic hydrops (EH) by systematic review and Meta-analysis. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio and area under summary receiver operating characteristic curves (AUC) were calculated. Subgroup analysis a...

The majority of patients with Meniere’s disease (MD) may be managed conservatively with medical therapy. Those who have symptoms refractory to medical management may benefit from surgery. Recently intratympanic gentamicin (IG) administration has gained widespread popularity. Different studies on the effectiveness of treatment with IG, including metaanalysis , document good results in the contro...

Research related to expanding and improving the clinical use of electrocochleography (ECochG) has been ongoing for 25 yr at the University of Kansas Medical Center. This article presents highlights of findings from our laboratory during this period that have contributed to current ECochG recording approaches and clinical applications. A review of new data related to improving the sensitivity of...

Background. Meniere's disease is characterized by refractory dizziness and hearing disturbance. We aimed to investigate the efficacy and tolerance of Diaoshi Jifa, a Chinese hand skill for treating dizziness in Meniere's disease. Methods. An open-labeled, randomized, controlled intervention trial was conducted. Twenty-seven patients diagnosed with Meniere's disease were randomly allocated to co...

OBJECTIVE Ménière's Disease (MD) is a chronic, non-life threatening inner ear disease, with attacks of disabling vertigo, progressive hearing loss, and tinnitus as the major symptoms. All three symptoms, separately or in combination, cause great distress and have a considerable impact on the quality of life of the patients. The aims of this study were to develop a disease-specific quality of li...

BACKGROUND The traditional approach to dizziness encourages providers to emphasize the type of dizziness. However, symptom types might substantially overlap in individual patients, thus limiting the clinical value of this approach. We aimed to describe the overlap of types of dizziness using a US nationally representative sample. METHODS The 2008 US National Health Interview Survey was examin...

In the last several years, a promising new approach has been suggested in the therapy of Ménière's disease (MD): the low-dose intratympanic gentamicin therapy. By titrating the desired vestibular inhibition by single injections and infrequent administration, side effects concerning hearing can be held on an acceptably low level, while disease-related symptoms are often successfully eliminated. ...

OBJECTIVE Determine the outcome of hearing in Meniere's Disease (MD) after antiviral treatment. STUDY DESIGN Prospective study. SETTING University Hospital. METHODS Thirty one new patients with a diagnosis of MD were treated with antiviral drugs during 2012. Acyclovir or valacyclovir was used depending on insurance coverage and cost. A standard dose of 800 mg (acyclovir) or 1g (valacyclov...