BACKGROUND AND PURPOSE Platinum coil embolization is one of the significant advances in interventional neuroradiologic techniques that has been introduced this decade. Our purpose was to evaluate the angiographic and histologic effects of collagen-coated platinum microcoil delivery in the canine artery. METHODS We embolized the bilateral internal maxillary arteries of 18 dogs; one uncoated an...

Introduction: Rhabdomyosarcoma (RMS) is a rare and aggressive mesenchymal tumor arising from skeletal muscle cells. Although it predominantly seen in children, can also affect adults. RMS typically presents as rapidly growing mass the head neck region, genitourinary tract, or extremities. Among these sites, cervical exceedingly has only been reported handful of cases. Case Presentation: In this...

Introduction: Diabetic kidney disease (DKD), one of the leading causes end-stage renal disease, has complex pathogenic mechanisms and few effective clinical therapies. DKD progression is accompanied by loss resident cells, followed chronic inflammation extracellular matrix deposition. Necroptosis a newly discovered form regulated cell death major intrinsic in certain diabetic complications such...

OBJECTIVE Successful animal and clinical implantation of decellularised heart valves has been performed in the pulmonary position. Comparable results have not yet been achieved for the aortic position with the high haemodynamic demands of the systemic circulation and the challenging implantation procedure. METHODS Allogenic aortic valves (n=10) were decellularised using detergents (decellular...

BACKGROUND Recent findings support a connection between mitochondrial dysfunction and activation of inflammatory pathways in articular cells. This study investigates in vivo in an acute model whether intra-articular administration of oligomycin, an inhibitor of mitochondrial function, induces an oxidative and inflammatory response in rat knee joints. METHODS Oligomycin was injected into the r...

AIM Prevalence and risk factors associated with intestinal parasites among children ≤ 12 years old in Nahavand county western Iran, was the objective of this search. BACKGROUND Intestinal parasites (IPs) are important health problems among most societies. METHODS This cross sectional study was carried out during 6 months from April to September 2014 in Nahavand County western Iran. Fecal sa...

After injury, inflammation, or degeneration, articular cartilage has limited self-repair ability. We aimed to explore the feasibility of repair of articular cartilage defects with tissue-engineered cartilage constructed by acellular cartilage matrices (ACMs) seeded with adipose-derived stem cells (ADSCs). The ADSCs were isolated from 3-month-old New Zealand albino rabbit by using collagenase an...

Pharmacognosy Research,2023,15,1,101-111.DOI:10.5530/097484900263Published:December 2022Type:Original ArticleAuthors:Deshraj Shyamkant Chumbhale, and Mahendra Shivshankar Khyade Author(s) affiliations:Deshraj Chumbhale1, Khyade2,* 1Department of Pharmacognosy, Amrutvahini College Pharmacy, Sangamner, Ahmednagar, Maharashtra, INDIA. 2Department Botany, Sangamner Nagarpalika Arts, D.J. Malpani Co...

BACKGROUND Ephrins and their related receptors have been implicated in some developmental events. We have demonstrated that ephrin-B2 (EFNB2) could play a role in knee joint pathology associated with osteoarthritis (OA). Here, we delineate the in vivo role of EFNB2 in musculoskeletal growth, development, and in OA using a cartilage-specific EFNB2 knockout (EFNB2(Col2)KO) mouse model. METHODS ...

AIM To study a rare clinical case of isolated primary osteoma localized in the frontal bone, provide its detailed clinical and pathomorphological analysis, and evaluate statistical indicators of occurrence frequency and localization of facial skeleton osteomas during 2006-2015. MATERIALS AND METHODS The retrospective case records analysis of patients undergoing treatment in the ma-xillofacial...