Background: Currently, cutaneous leishmaniasis (CL) as a parasitic disease is treated with Glucantime and Pentostam in most of the endemic countries. This study aimed to identify factors affecting the glucantime therapy duration rate in patients with CL using a survival analysis model. Methods: This retrospective descriptive-analytic study was conducted on 1017 CL patients that were referred t...

Abstract Background verrucae are benign proliferations seen in skin and mucosae due to infection with papillomaviruses. Aim Objectives the aim of this work is compare clinical efficacy intra-lesional 2% zinc sulfate solution vs intralesional vitamin D treatment planter warts, Subjects Methods Three armed single blinded randomized trial included 105 patients presented Patients were all recruited...

This paper in short reviews general indications, doses and routes of administration of glucocorticoid therapy in rheumatology. It presents greater detail concerning intralesional and intra-articular glucocorticoid injections.

Stricture frequently occurs after endoscopic submucosal dissection (ESD) for superficial esophageal carcinoma with near- or whole-circumferential mucosal defects, and post-ESD stricture is difficult to treat and usually requires multiple sessions of endoscopic balloon dilatation. Intralesional steroid injection has previously been used to prevent stricture; however, there have been few experien...

Method: This is a prospective, randomized, open trial study (from Iran) from September 2008 to September 2010, including 50 patients (25 patients in the combined imiquimod and cryotherapy group and 25 patients in the intralesional MA group). Patients were randomly assigned to receive combined cryotherapy biweekly with imiquimod three times per week or intralesional MA weekly until complete cure...

Salivary mucocele is a common lesion derived from minor salivary glands with various surgical or nonsurgical treatment modalities. To evaluate the effect of a highly potent corticosteroid (dexamethasone) in the management of salivary mucocele, we performed intralesional injection of dexamethasone in nine patients with labial mucocele. Complete healing of lesions observed in seven of nine patien...

BACKGROUND Pentavalent antimony is the agent recommended for treatment of cutaneous leishmaniasis (CL). Its use is problematic, because it is expensive and because of the potential for drug-associated adverse effects during a lengthy and painful treatment course. METHODS We tested the efficacy of thermotherapy for the treatment of CL due to Leishmania tropica in a randomized, controlled trial...

Treatment of cutaneous leishmaniasis is often difficult. Even though most cutaneous lesions will heal spontaneously, their duration cannot be predicted in an individual case. In general, only large, multiple or diffuse lesions of the face, head and neck need to be considered for therapeutic intervention. Pentavalent antimonials (sodium stibogluconate and meglumine antimoniate) administered intr...

OBJECTIVE To compare intralesional versus oral chloroquine in cutaneous leishmaniasis and determine the cure rate, duration of treatment, and total dose of drug. STUDY DESIGN Randomized controlled study. PLACE AND DURATION OF STUDY Department of Dermatology, Sheikh Zayed Medical College/Hospital, Rahim Yar Khan, from November 2013 to June 2014. METHODOLOGY Consecutive 86 patients of cutan...