High altitude pulmonary edema (HAPE) susceptibility is associated with EGLN1 polymorphisms, we hypothesized that HAPE-susceptible (HAPE-S, had HAPE episode in past) subjects may exhibit abnormal HIF1α levels in normoxic conditions. We measured HIF1α levels in HAPE-S and HAPE resistant (HAPE-R, no HAPE episode) individuals with similar pulmonary functions. Hemodynamic responses were also measure...

BACKGROUND A capable expression vector is mainly characterized by its production efficiency, stability and induction response. These features can be influenced by a variation of modifications and versatile genetic modules. RESULTS We examined miscellaneous variations of a rhaPBAD expression vector. The introduction of a stem loop into the translation initiation region of the rhaPBAD promoter ...

Effect of intracerebroventricularly (icv) or subcutaneously (sc) injected L-arginine (L-Arg) on memory was determined using the procedure of passive avoidance test. Moreover, locomotor and exploratory activity was determined in rats in an open field test. We found that either the peripheral (sc) or icv administration of L-Arg significantly prolonged latency time in the passive avoidance test. T...

BACKGROUND Nasal carriage of Staphylococcus aureus is becoming an increasing problem among healthcare workers and community individuals. OBJECTIVES To determine the prevalence of methicillin-resistant S. aureus (MRSA) nasal colonization and inducible clindamycin resistance (ICR) of S. aureus among healthcare workers at Soba University Hospital and community members in Khartoum State, Sudan. ...

The surveillance of Device associated infections in ICUs can reduce incidence of Nosocomial infections (NIs), healthcare cost & a better control of infections. Aims & Objectives: To know the occurrence of device associated infection rate in ICU and to know the bacterial profile of various devices associated infections. Materials and Methods: This study was conducted between October 2011 to May ...

Sir, Urticaria is an immunologically mediated hypersensitivity reaction developing in both sexes. Although it may occur at any age, young females are more frequently affected [1]. Acute urticaria, shorter than six weeks, generally self-limited. In contrast, a patient with urticaria lasting weeks classified as having chronic urticaria. Patients be into either inducible or spontaneous (CSU). true...

BACKGROUND Data on outcomes after catheter ablation of ventricular tachycardia (VT) in patients with nonischemic dilated cardiomyopathy (NIDCM) are insufficient. We aimed to investigate the effects of successful catheter ablation of VT on cardiac mortality in patients with NIDCM. METHODS AND RESULTS One hundred two patients with NIDCM (86 men; mean age, 58.8±15.2 years; mean ejection fraction...

INTRODUCTION Clindamycin is an alternative antibiotic in the treatment of Staphylococcus aureus (S.aureus) infections, both in infections by methicillin susceptible and resistant (MSSA and MRSA) strains. The major problem of use of clindamycin for staphylococcal infections is the presence of inducible clindamycin resistance that can lead to treatment failure in such infections. AIM To determi...

Abstract Objective This study aimed to clarify the association between both hypoxia-inducible factor-1α and glucose transporter type-1 expression survival outcome in advanced pharyngeal cancer without human papillomavirus infection. Method Twenty-five oropharyngeal 55 hypopharyngeal patients infection were enrolled. All had stage III–IV lesions underwent concurrent chemoradiotherapy or surgery....