Introduction: The in situ immune response in skin biopsies from patients affected by autoimmune skin blistering diseases (ABD) is not well characterized. Aim: Our investigation attempts to immunophenotype cells in lesional skin in several ABD, utilizing immunohistochemistry (ICH). Methods: We tested by IHC for CD4, CD8, CD19, CD20, CD45, CD56/NCAM, PAX-5, granzyme B, myeloperoxidase, neutrophil...

Hox genes that determine anteroposterior body axis formation in all bilaterians are often found to have partially overlapping expression pattern. Since posterior genes dominate over anterior Hox genes in the region of co-expression, the anterior Hox genes are thought to have no function in such regions. In this study we show that two Hox genes have distinct and essential functions in the same c...

Rationale: Albumin-binding carriers have been shown to target cytotoxic T lymphocyte (CTL) vaccines to lymph nodes (LNs) and improve the efficacy of the vaccines. However, it was not clear whether the improved efficacy is solely due to the LN targeting, which prompted this study. Methods: First, we generated a fusion protein consisting of an albumin-binding domain (ABD) and an immune-tolerant e...

the oldest works of muslim scholars in the fields of kalām , ḥadīth and tafsīr during the 2nd and 3rd centuries ah rarely offer an explicit basis for regarding the qur’ān as an inimitable miracle of the prophet. however, the issue appears fully fledged in the works of scholars such as al-bāqillānī, qāḍī ‘abd al-jabbār and al-sharīf al- murtaḍā. this silence in the early islamic centuries, when ...

The problem in this study it is the reason why Prophet Khidr repeated his words -You will not patient with me - to prophet Moses, even though Moses was known as intelligent prophet. This research uses theory of ijaz and ithnab (brevity redundancy) science rhetoric. finds abbreviated word types extended types. a qualitative approach that descriptive through literature review. Researcher found th...

Abu-al-Hassan, Ala-a`Ddeen Ali Ibn Abe`l-Hazm Ibn a`Nnafees al-Qurashi a`Ddimashqi (607-687 A.H.) was born in Damascus, wherein he grew up and was occupied studying sciences as syntax, jurisprudence, medicine, theology, tradition, logic, etc. His most well known masters in medicine were Muhadhdhib a`Ddeen a`Ddakhwar and Umran Israeli. After completing his studies, he left Damascus for Cairo, wh...

Abu-al-Hassan, Ala-a`Ddeen Ali Ibn Abe`l-Hazm Ibn a`Nnafees al-Qurashi a`Ddimashqi (607-687 A.H.) was born in Damascus, wherein he grew up and was occupied studying sciences as syntax, jurisprudence, medicine, theology, tradition, logic, etc. His most well known masters in medicine were Muhadhdhib a`Ddeen a`Ddakhwar and Umran Israeli. After completing his studies, he left Damascus for Cairo, wh...