Various medicinal plants are used in traditional system of medicine to treat various diseases and many of these plants have been evaluated for their different pharmacological activities. Borassus Flabellife is one among them. The present study was planned to investigate Antiinflammatory effect of Borassus Flabellife ethanolic extract of root. Acute inflammation was produced by injecting 0.1 ml ...

Objective: To study the anti-arthritic activity of Acetone Extract of fruits of Terminalia chebula (TCE) in wistar rats in an experimental model of rheumatoid arthritis. Materials and methods: After necessary approval from Institutional Animal Ethics Committee (IAEC), 28 wistar albino rats of either sex (150-200gm) were randomly divide into 7 groups. Arthritis was induced in all animals by intr...

The medicinal plants have been selected for thorough studies from indigenous folk medicines, Ayurvedic, Unani and Siddha systems of medicines. The aim of this study deals with the comparative evaluation of anti-inflammatory activity of the bark of Ficus bengalensis in plants of different age. The anti-inflammatory activity was evaluated by rat paw edema model induced by carrageenan for acute in...

Four new 1,2,3-triazole phthalimide derivatives with a potent anti-inflammatory activity have been synthesized in the good yields by the 1,3-dipolar cycloaddition reaction from N-(azido-alkyl)phthalimides and terminal alkynes. The anti-inflammatory activity was determined by injecting carrageenan through the plantar tissue of the right hind paw of Swiss white mice to produce inflammation. All t...

The purpose of this study was to test the effect of high voltage stimulation (HVS) on edema reduction in the rat hindpaw. The animals were divided into a control group (n = 20) and a treated group (n = 20). The right hindpaw volume was measured, and then the animal's paw was traumatized. The animals in the treated group were treated with HVS at 24, 48, and 72 hours posttrauma. Paw volume measur...

Objective: Rheumatoid arthritis (RA) is a progressive, disabling and autoimmune disorder characterized by pain, swelling and stiffness of the synovial joints. Gloriosa superba Linn. (familyLiliaceae) is one of the herbaceous climbers distributed throughout Western Ghats and well documented traditionally in Ayurveda system of medicine for various ailments like inflammation, gout, gonorrhea, lepr...

Inflammation is the local response of living mammalian tissues to injury due to any agent. It is the body defence reaction in order to eliminate or limit the spread of injurious agent, followed by removel of the necrosed cells and tissues, but the sign and symptoms which are produced during healing process can’t tolerable. The present study was aimed to investigate the anti-inflammatory activit...

Complex regional pain syndrome-type I (CRPS-I; reflex sympathetic dystrophy) is a chronic pain condition that usually follows a deep-tissue injury such as fracture or sprain. The cause of the pain is unknown. We have developed an animal model (chronic post-ischemia pain) that creates CRPS-I-like symptomatology. The model is produced by occluding the blood flow to one hind paw for 3 hours under ...

background: rheumatoid arthritis is a type of inflammatory pain and is an autoimmune and chronic inflammatory disease which can lead to hyperalgesia, edema and decreased motor activity in affected area. mesenchymal stem cells conditioned medium (msc-cm) has anti-inflammatory mediators which can regulate the immune responses, alleviate inflammatory symptoms and has a paracrine effects too. the a...

INTRODUCTION Tricyclic antidepressants are used in the treatment of various pain syndromes. The antidepressant clomipramine inhibits predominantly the reuptake of serotonin in the central nervous system. The mechanism of its analgesic effect is not fully understood. The AIM of the present study was to find experimentally any dose-effect dependence in the analgesic effect of clomipramine and the...