نتایج جستجو برای: guanidine

تعداد نتایج: 3719  

2018

Submit Manuscript | http://medcraveonline.com classes of pyrimidines. The pharmaceutical importance of these compounds lies on the fact that they can be effectively used as analgesics, anti-inflammatory, anticonvulsant, insecticidal, herbicidal, antitubercular, anticancer and antidiabetic agents [4-6]. Also, the pyrimidine and aminopyrimidine structures are frequently-occurring motifs in commer...

Journal: :The Journal of pharmacology and experimental therapeutics 2015
Heather D Snell Eric B Gonzales

Amiloride, a diuretic used in the treatment of hypertension and congestive heart failure, and 2-guanidine-4-methylquinazoline (GMQ) are guanidine compounds that modulate acid-sensing ion channels. Both compounds have demonstrated affinity for a variety of membrane proteins, including members of the Cys-loop family of ligand-gated ion channels, such as the heteromeric GABA-A αβγ receptors. The a...

2003
P. GREENSTEIN

The denaturation of certain proteins is characterized in part by the appearance of titratable sulfhydryl groups (8,11, 13).’ Moreover, the proportion of these groups which appears in any one protein is dependent upon the method of denaturation employed (3,5,6). Proteins dissolved in solutions of urea, guanidine hydrochloride, and related substances show widely different amounts of sulfhydryl gr...

2015
Heather D. Snell Eric B. Gonzales

Amiloride, a diuretic used in the treatment of hypertension and congestive heart failure, and 2-guanidine-4-methylquinazoline (GMQ) are guanidine compounds that modulate acid-sensing ion channels. Both compounds have demonstrated affinity for a variety of membrane proteins, including members of the Cysloop family of ligand-gated ion channels, such as the heteromeric GABA-A abg receptors. The ac...

2002
C. J. WEBER

The extremely sensitive color reaction given by certain guanidine derivatives with ar-naphthol and sodium hypochlorite, which was observed by Sakaguchi (1925), has been extensively employed as a qualitative test for arginine. The greatest obstacle in a quantitative application of this reaction is its slow rate of color development with the probable destruction of some of the guanidine group by ...

Journal: :Journal of Biological Chemistry 1966

Journal: :The Journal of the Society of Chemical Industry, Japan 1949

Journal: :Journal of Clinical Investigation 1934

Journal: :Biochemistry 1976
F Ahmad A Salahuddin

The guanidine hydrochloride induced unfolding of the major fraction of ovalbumin (i.e. A1 which contains two phosphate groups and constitutes about 77% of the total protein) was investigated systematically by difference spectran and viscosity measurements. As judged by the intrinsic viscosity (3.9 ml/g), the native protein conformation is compact and globular. Difference spectral results showed...

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