The objective of this study was to compare three superovulation protocols in dromedary camels. Follicular waves of dromedary camel donors (n=6) were synchronized using two GnRH injections. Superovulation was initiated 2 days after the second injection (day 0 of experiment). The experiment was conducted using change over design, where all females received three superovulation treatments one afte...

Multiple pregnancies and ovarian hyper stimulation syndrome (OHSS) are the most serious complications of ovarian stimulation and IVF. Indeed, they are more or less the only ones. OHSS can effectively be prevented in three stages: Before stimulation, during stimulation and at ET. Before stimulation patients should be assessed as to age, the ovarian follicular count and/or anti mullerian hormone ...

Abstract Study question Could exogenous progestin replace the use of an antagonist GnRH (GNRH-antagonist) without any effects on embryo morphokinetics and implantation rate in freeze-all cycles? Summary answer Exogenous leads to slower development increased cyclés cancellation rate, with when compared cycles using GnRH-antagonist. What is known already Improvements cryopreservation techniques a...

Abstract Study question Does desogestrel an option for LH suppression during controlled ovarian stimulation oocyte vitrification? Summary answer This new did not affect FORT and, consequently, the number of collected oocytes vitrification. What is known already Traditionally, achieved by using a gonadotropin-releasing hormone (GnRH) analogue. However, improved cryopreservation techniques and fr...

We read the article by Minig et al. [1] with great interest. The authors evaluated the efficacy of levonorgestrel-releasing intrauterine device (LNG-IUD) and gonadotropin-releasing hormone (GnRH) for treating patients with atypical endometrial hyperplasia (AEH) or early-stage endometrial cancer, grade I, who wanted to maintain their fertility. The research demonstrated that the combined therapy...

In the present paper the role of GnRH in the ultrashort loop of the negative feedback action on GnRH secretion was evaluated on the molecular level by the Real-time PCR technique. Specifically, the effect of GnRH infused into the third cerebral ventricle on the expression of GnRH and GnRH receptor (GnRH-R) genes was analyzed in the hypothalamic-pituitary unit of anestrous ewes. GnRH did not sig...

IntroductionObesity has detrimental influences on women reproductive health. There is little experience in optimizing controlled ovarian hyperstimulation (COH) protocols to treat Chinese obese patients who are undergoing vitro fertilization and embryo transfer (IVF-ET) therapy.MethodsThe clinical outcome differences were retrospectively analyzed among received gonadotrophin-releasing hormone ag...

It has become a general notion that there are multiple GnRH systems in the vertebrate brains. To measure GnRH release activities from different GnRH systems, we conducted a static incubation of brain-pituitary slices under various conditions, and GnRH released into the incubation medium was measured by RIA. The slices were divided into two parts, one containing GnRH neurons in the preoptic area...