Esophageal cancer is one of the most aggressive malignant neoplasms gastrointestinal tract, occupying eighth place in structure morbidity worldwide. Despite comprehensive approaches to treatment, mortality continues grow both gender groups, which moves this pathology sixth position from tumors. A lot patients undergo radiation therapy preoperative period or an independent version due peculiarit...

Dubowitz syndrome was first described in 1965 by the English physician Dr. Victor Dubowitz. This genetic disorder causes growth retardation both before and after birth. It is primarily diagnosed through the distinctive facial features of affected individuals, including a small triangular-shaped face with a high forehead and wide-set, slitted eyes. The main method of diagnosis is through identif...

Esophageal cancer poses an interesting challenge for oncologists. Esophageal squamous cell cancer has the most varied geographical incidence of any cancer, suggesting the existence of critically important environmental and molecular epidemiologic factors. These factors remain largely unrecognized. Equally puzzling is the dramatic increase in the incidence of adenocarcinomas of the esophagus and...

BACKGROUND AND STUDY AIMS  Cervical esophageal cancer (CEC) is a less common form of cancer and often locally advanced at the time of diagnosis; thus, survival rates for patients with CEC remain poor. However, no reports exist on results of endoscopic submucosal dissection (ESD) for superficial cancer at the cervical esophagus. The aim of this retrospective study was to elucidate the clinicopat...

A hospital-based case-control study of upper aerodigestive tract tumors was conducted between June 1986 and June 1989 in Northern Italy. One hundred fifty-seven male cases of oral cavity cancer, 134 of pharyngeal cancer, 162 of laryngeal cancer, and 288 of esophageal cancer, and 1272 male inpatients with acute conditions unrelated to tobacco and alcohol were interviewed. Odds ratios for current...

The only treatment for the terminal symptoms of the laryngeal cancer is to remove the larynx including vocal cords, which mean that the patient loses his voice. Esophageal speech is a method of speech production using an esophagus. An air inhaled in the upper esophagus generates the esophagus vibration to produce a belch-like sound that can be shaped into speech. Although this method has diffic...

In recent years, endoscopic therapy of early Bar− rett’s esophagus neoplasia has become a safe and effective alternative to esophagectomy [1 ± 4]. Only patients with high−grade intraepithelial neoplasia (HGIN) or mucosal cancer are eligible for curative endoscopic treatment. Lesions that invade the submucosa are associated with a sig− nificant risk of lymph node metastases and are therefore pre...

Neoplasms progress to cancer through a process of natural selection. The rate of evolution, and thus progression is determined by three parameters: mutation rate, population size of the evolving neoplastic cells, and intensity of selection or rate of clonal expansion. All three parameters are reviewed in the context of Barrett's esophagus, a pre-malignant neoplasm. Although Barrett's esophagus ...

The sign of Leser-Trélat is a rare paraneoplastic phenomenon marked by accelerated onset of multiple seborrheic keratoses. The occurrence of the sign often points towards underlying visceral malignancies which in a majority are adenocarcinomas of the gastrointestinal tract. We report this case of a 65-year-old man who presented with sign of Leser-Trélat and was diagnosed with poorly differentia...