We describe a patient with a pure motor chronic demyelinating polyneuropathy with an IgM monoclonal component showing anti-GM2, GalNAc-GD1a and GalNAc-GM1b reactivity whose common epitope appears to be -[GalNAcbeta1-4Gal(3-2alphaNeuAc)beta1]. We used intracellular recording to study how IgM from this patient affected neurotransmitter release in the mouse diaphragm in vitro. Adding serum (and sp...

PURPOSE AND METHODS Postmyelography CT studies of 84 patients with 114 thoracic herniated disks were reviewed for endplate irregularity, sclerosis, and/or disk-space calcification that could suggest a migratory path of the herniated fragment. RESULTS Abnormal straight or curvilinear densities (the "nuclear trial sign") were present at the level of the disk or endplate in 46% of the cases. MR ...

Botulinum toxin type A (BTX) injections are frequently used in children with cerebral palsy (CP) to control spasticity. Injection variables still lead to variable outcomes of this treatment. Using instrumented spasticity assessment and muscle volume assessment the most effective location of the injection was demonstrated for gracilis and psoas muscles in children with CP. It was found that this...

In this paper, a sweeping jet is applied to control the afterbody vortices behind slanted-base cylinder for first time at Reynolds numbers from 87 000 200 000. The effects are examined using stereo particle image velocimetry and surface pressure measurements with momentum coefficient (C ? ) varying 0.056 0.893. It found that results in increasingly diffused larger as C increases. While an incre...

Using the mouse passive transfer model, the effects of purified human myasthenic immunoglobulin G and of the monovalent Fab fragment on neuromuscular junctions were investigated. Treatment with IgG markedly reduced amplitudes of miniature endplate potentials. When Fab fragments were transferred alone or with subsequent addition of IgG no neuromuscular transmission block was induced. Myasthentic...