نتایج جستجو برای: embryonic implantation

تعداد نتایج: 138584  

2016
William A. Pastor Di Chen Wanlu Liu Kathrin Plath Steven E. Jacobsen Amander T. Clark Rachel Kim Anna Sahakyan Anastasia Lukianchikov

Graphical Abstract Highlights d Reversion or derivation of hESCs in 5iLAF results in SSEA4-negative cells d SSEA4-negative hESCs show gene expression consistent with naive pluripotency d Naive hESCs show lost ''memory'' of gamete and blastocyst methylation d Imprinting is lost in naive hESCs In Brief Pastor and colleagues show that reversion of primed hESCs in 5iLAF, or derivation of hESCs in 5...

2012
Kazuhiro Kawamura Yuan Chen Yimin Shu Yuan Cheng Jie Qiao Barry Behr Renee A. Reijo. Pera Aaron J. W. Hsueh

Studies using animal models demonstrated the importance of autocrine/paracrine factors secreted by preimplantation embryos and reproductive tracts for embryonic development and implantation. Although in vitro fertilization-embryo transfer (IVF-ET) is an established procedure, there is no evidence that present culture conditions are optimal for human early embryonic development. In this study, k...

Journal: :Human reproduction update 2011
Hakan Cakmak Hugh S Taylor

BACKGROUND Implantation is a complex initial step in the establishment of a successful pregnancy. Although embryo quality is an important determinant of implantation, temporally coordinated differentiation of endometrial cells to attain uterine receptivity and a synchronized dialog between maternal and embryonic tissues are crucial. The exact mechanism of implantation failure is still poorly un...

2010
Yacine Kharraz Pierre-Adrien Salmand Anne Camus Jacques Auriol Cyril Gueydan Véronique Kruys Dominique Morello

BACKGROUND TIA-1-related (TIAR) protein is a shuttling RNA-binding protein involved in several steps of RNA metabolism. While in the nucleus TIAR participates to alternative splicing events, in the cytoplasm TIAR acts as a translational repressor on specific transcripts such as those containing AU-Rich Elements (AREs). Due to its ability to assemble abortive pre-initiation complexes coalescing ...

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