background: aggressive embryo and receptive endometrium are necessary for successful implantation. on this time endometrium transformates to receptive state, which permits embryonic implantation. studies about embryonic implantation and endometrial receptivity are always a hot spot in the field of reproductive medicine. objective: to investigate the expression pattern of meis1 during peri-impla...

Abstract Following implantation, the human embryo undergoes major morphogenetic transformations that establish future body plan. While molecular events underpinning this process are established in mice, they remain unknown humans. Here we characterise key of morphogenesis, period between implantation and gastrulation, using single-cell analyses functional studies. First, embryonic epiblast cell...

The preimplantation embryo produces several factors during its development to signal its presence to the maternal organism. This paper will focus on the role of two distinctive cytokine and growth factor systems (interleukin-1 (IL-1) system and the vascular endothelial growth factor (VEGF) system) during early embryonic development and implantation. IL-1 receptor is expressed in the endometrium...

Embryonic implantation is a key step in the establishment of pregnancy. In present work, we have carried out an in-depth proteomic analysis secretome (extracellular vesicles and soluble proteins) two bovine blastocysts embryonic trophectoderm primary cultures (BBT), confirming different epithelial–mesenchymal transition stages these cells. BBT-secretomes contain early pregnancy-related proteins...

The success of reproduction, although gradually increasing over the years, many couples also had been left frustrated following repeated failed attempts. Clinicians who treated unsuccessful couples often face a challenge. The probable causes of repeated IVF failures classified as: reduced endometrial receptivity, embryonic defects or multifactorial causes. Intrauterine and endometrial integrity...

This investigation follows the development of embryos in the uteri of mice in which the differentiation of the implantation chamber has been retarded by the administration of actinomycin D before implantation. For the first 48 h after the induction of implantation both embryonic and extra-embryonic parts of the blastocyst develop, but after 72 h the embryonic parts cease to grow and die. The gi...

Cover illustration: The cover image is based on the Research Article Repetitive short-pulsed illumination efficiently activates photoactivatable-Cre as continuous in embryonic stem cells and pre-implantation embryos of transgenic mouse by Kanae Kishi et al., https://doi.org/10.1002/dvg.23457.