Metastatic breast cancer is the second leading cause of cancerrelated deaths among women. Triple-negative breast cancer (TNBC) is a highly aggressive subcategory of breast cancer and currently lacks well-defined molecular targets for effective targeted therapies. Disease relapse, metastasis, and drug resistance render standard chemotherapy ineffective in the treatment of TNBC. Because previous ...

BACKGROUND Cigarette smoking causes cardiovascular disease and activates markers of endothelial dysfunction or injury. We investigated the nailfold capillary blood velocity (NCV) in cigarette smokers compared to non-smokers. METHODS Forty-eight men (eighteen non-smokers and thirty smokers) were recruited. We measured NCV using nailfold capillary microscopy and exhaled carbon monoxide (ECO) co...

Eco-P colonies are constructed as natural extension of P colonies with dynamical evolution of environment. P colonies are one of the kind of computational models based on independent autonomous agents represented by membrane systems working and evolving in a shared environment. These acts are based on the set of program associated with every agent. There are two types of agents in eco-P colonie...

Silica gel was found to efficiently promote the rearrangement of allylic acetates into their most stable regioisomers under microwave irradiation. The reaction is easy to perform and eco-friendly. This method was applied to the metal-free synthesis of 1,3-enynes.

An effective and eco friendly procedure under microwave irradiation, for synthesis of symmetrical disubstituted alkyl and aryl ureas from amine hydrochlorides using water as solvent medium has been developed. Based on molecular docking studies on HIV-1 gp120, synthesized compounds were evaluated for HIV-1 gp120 – CD4 binding inhibition and these molecules showed micro molar range (0.047 μM to 4...

A microwave-promoted new easy, efficient, clean and environmentally benign method for the synthesis of 1,7naphthyridineand its derivatives from 2-cyano-3-pyridylacetonitrile has been developed. The desired products were isolated in excellent yields and high purity under eco-friendly conditions.The synthesized compounds were characterized by the IR, UV-Visible and H NMR spectral analyses along w...

Altered precipitation regimes significantly affect ecosystem structure and function in arid and semi-arid regions. In order to investigate effects of precipitation changes on natural grassland community in the semi-arid Loess Plateau, the current research examined eco-physiological characteristics of two co-dominant species (i.e., Bothriochloa ischaemum and Lespedeza davurica) and community com...

Eco-certification has become an increasingly popular market-based tool in the endeavor to reduce negative environmental impacts from fisheries and aquaculture. In this study, we aimed at investigating which psychological consumer characteristics influence demand for eco-labeled seafood by correlating consumers’ stated purchasing of eco-labeled seafood to nine variables: environmental knowledge ...

In this study, individuals’ levels of personal responsibility and actual behavior towards protecting the environment were studied to examine the effects both these variables would have on the individuals’ environmental guilt or “eco-guilt.” The research measured 95 participants’ personal eco-guilt through surveys. Half received a manipulation that was used to make them feel responsible for thei...