نتایج جستجو برای: dosage effects
تعداد نتایج: 1626474 فیلتر نتایج به سال:
Introduction and Purpose: Discharge of the wastewater containing reactive dyes into water resources can have detrimental effects on the environment and to the human health due to their carcinogenic, mutagenic, and toxic nature. The present study was performed to evaluate the efficiency of rosewater waste in removal of reactive blue 19 dye from aqueous solutions. Methods: In this experimental st...
Gene expression can be modulated in two opposite directions, towards higher or lower amounts of product. How do diametric changes in gene dosage influence neurological development and function? Recent studies of transgenic and knockout mouse models, genomic copy-number variants, imprinted-gene expression alterations, and sex-chromosome aneuploidies are revealing examples of 'mirror-extreme' bra...
This article investigates drug dosage individualization when the patient population can be described with a random-effects linear model of a continuous pharmacokinetic or pharmacodynamic response. Specifically, we show through both decision-theoretic arguments and simulations that a published clinical algorithm may produce better individualized dosages than some traditional methods of therapeut...
This study investigated the effects of administration of parathyroid hormone (PTH) at different dosages and schedules on bone regeneration in critical-size bone defects in rat calvariae. After calvarial defects had been prepared in 50 rats, they were divided into five treatment groups: 15 µg/kg PTH daily (PTH-15), 35 µg/kg PTH three times per week (PTH-35), 105 µg/kg once per week (PTH-105-1), ...
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