The relationship between varicocele and hypogonadism becomes clearer everyday thanks to the most recent literature, particularly with regards impact of repair on serum testosterone level improvement in hypogonadal patients. We selected English articles published from 1964 September 2021. search terms “varicocele” “hypogonadism” were used as filters. A total 102 studies have been obtained. For m...

Background: To compare the c l in ica l e f fec t o f varicocelectomy treatment between patients who were diagnosed as secondary varicocele caused by nutcracker syndrome (NCS) and primary varicocele patients. Methods: The secondary varicocele patients combined with NCS admitted in our hospital were systematically reviewed. All these patients had no obvious related symptoms such as gross hematur...

OBJECTIVE To evaluate varicocele effects on conventional semen parameters: sperm DNA fragmentation, chromatin packaging, mitochondrial membrane potential (MMP) and sperm apoptosis. METHODS A cross-sectional study was carried out with semen samples from 2,399 men of couples who attended an infertility clinic. A total of 16.3% (391/2399) of the men were diagnosed with varicocele by a urologist....

Varicocele is characterized by abnormal tortuosity and dilation of the veins of the pampiniform plexus within the spermatic cord. Although several reports show the mechanisms by which the varicocele exerts its infertility impact, the exact pathophysiology for varicocele-induced inflammation and its relationship with testicular endocrine disruption remain largely unknown. This review article wil...

BACKGROUND Prepubertal varicocele has the most devastating effects on the testes. Oxidative stress is the major cause leading to infertility in varicocele. The antioxidant properties of Flaxseed (FS) treatment in some oxidative diseases have been reported. OBJECTIVE This study aimed to evaluate the antioxidant effect of FS in prepubertal rats with experimental varicocele. MATERIALS AND METH...

427 patients with varicocele ranging in age from 14 to more than 35 years underwent surgical operation during a 10 year period (1977-1986). 190 (44.5%) were referred for infertility and 365 had left-sided varicoceles (85.5%). No relationship was found between infertility and the grade of varicocele. Clinical features of prostatitis were often present. Semen analyses were performed in 37% o...

BACKGROUND We examined the impact of the number of veins ligated during varicocelectomy on post-surgical improvement of pain in a group of men presenting with clinical varicocele and pain as an indication for surgery. METHODS This is a retrospective study of patients presenting with clinical left varicocele to the male infertility unit at a teaching hospital in Qatar. Files of all patients wh...

Sperm DNA integrity is of vital importance for foetal development and birth of healthy offspring. Oxidative stress and consequent DNA damage are the major cause of decline in semen quality in men with varicocele. A preliminary study was conducted on 11 men with clinical varicocele who also had high levels of reactive oxygen species (ROS), to assess DNA damage in sperms and ROS levels before and...

BACKGROUND The etiology of varicocele, a common cause of male factor infertility, remains unclear. Proteomic changes responsible for the underlying pathology of unilateral varicocele have not been evaluated. The objective of this prospective study was to employ proteomic techniques and bioinformatic tools to identify and analyze proteins of interest in infertile men with unilateral varicocele. ...

427 patients with varicocele ranging in age from 14 to more than 35 years underwent surgical operation during a 10 year period (1977-1986). 190 (44.5%) were referred for infertility and 365 had left-sided varicoceles (85.5%). no relationship was found between infertility and the grade of varicocele. clinical features of prostatitis were often present. semen analyses were performed in 37% of pat...