BACKGROUND Pediatric multiple sclerosis (MS) represents approximately 5% of the MS population; information regarding clinical features is slowly accumulating. Cognitive and psychiatric impairments frequently occur, but remain poorly understood. OBJECTIVES To describe psychiatric diagnoses among children with MS referred for psychiatric assessment and their relation to cognitive impairment. ...

OBJECTIVE To estimate the prevalence of World Health Organization-defined chronic suppurative otitis media (CSOM) and mild hearing impairment in a population representative sample of school-entry age children in rural Malawi. A secondary objective was to explore factors associated with CSOM in this population. METHODS We performed a community-based cross-sectional study of children aged 4-6 y...

: Dementia and cognitive impairment (CI) are some of the common problems associated with ageing. However, a lot other factors apart from ageing can increase this risk. In study, prevalence CI its correlation different sociodemographic clinical was assessed among patients attending outpatient department geriatric healthcare facility. A total 240 elderly OPD (>60 years) having recovered a...

BACKGROUND There is current interest in exploring the different subtypes of mild cognitive impairment (MCI), in terms of both their epidemiology and their cognitive profile. AIMS To examine the frequency of MCI subtypes presenting to a memory clinic and to document detailed neuropsychological profiles of patients with the amnestic subtype. METHOD Consecutive tertiary referrals (n=187) were ...

Sleep is essential for healthy brain function and plasticity underlying learning and memory. In the context of physical impairment such as following a stroke, sleep may be particularly important for supporting critical recovery of motor function through similar processes of reorganization in the brain. Despite a link between stroke and poor sleep, current approaches to rehabilitative care often...

In multiple sclerosis studies, lesion volume (or load) derived from conventional T2 imaging correlates modestly with clinical assessment. Determining which specific white matter pathways are impacted by lesions may provide additional insights regarding task-specific impairment. Using diffusion MRI, we introduce a set of tract-based metrics that go beyond traditional load approaches and show how...

Background Hypothyroidism is a highly prevalent disease and has been associated with deficits in cognitive performance. It generally accepted that these could be related to psychiatric symptoms. Hormone replacement therapy the gold standard treatment for primary hypothyroidism, it appears effective correcting serum thyrotropin (TSH) values thyroid hormone profile. Despite correction of hormonal...

Poor insight is associated with impaired cognitive function in psychosis. Whether poor clinical insight overlaps with other aspects of self-awareness in schizophrenia, such as cognitive self-awareness, is unclear. We investigated whether awareness of clinical state ("clinical insight") and awareness of cognitive deficits ("cognitive insight") overlap in schizophrenia in a sample of 51 stabilize...

This article discusses outcomes research in physical therapy and places its conceptual roots within the work on quality-of-care assessment. An argument is advanced that the outcomes research movement in medicine has stimulated clinical researchers in physical therapy to address disability outcomes in addition to traditional impairment outcomes. If physical therapy clinical research moves beyond...

There is now growing evidence that parkinsonism and other extrapyramidal signs are highly prevalent in patients with first-episode psychosis who have never been exposed to antipsychotic drugs. However, the neurocognitive correlates of parkinsonism in this population remained to be clarified. A sample comprising 100 consecutive drug-naive patients with first-episode psychosis were enrolled on th...