Areduction in low-density lipoprotein (LDL) cholesterol lowers coronary heart disease (CHD) by 24% to 31% in subjects with prevalent CHD; this reduction occurs with the use of several statins, including simvastatin1 and pravastatin.2,3 Additional reductions in CHD could come from further reductions in LDL cholesterol, as was suggested by the Post Coronary Artery Bypass Graft clinical trial (POS...

abstract   background: irregular working hours, including night work and shift work, have been found to be associated with alteration in various levels of biochemical factors. and some studies have showed association between shift work and blood biochemical disturbances in blood. in this epidemiological study we investigated, whether regular schedule of working hours can minimize the associated...

Present study was conducted to observe the effect of cholesterol and oxidized cholesterol (7beta-hydroxycholesterol,7beta-OH) on the nitric oxide (NO) production and the redox ratio by lipopolysaccharide-stimulated macrophages. Dose-dependent decrease in NO levels was seen with both cholesterol and 7beta-OH at different incubation intervals (6,12,18,24 hr) and concentrations (2.5,5,7.5microg/ml...

1. Mice when fed a cholesterol/choline-supplemented diet for 4 weeks developed histologically fatty livers. This lipid overloading was associated with an increase in hepatic concentration of connective tissues. 2. Both histological and biochemical abnormalities regressed on stopping the cholesterol diet for another 4 weeks. With continuing feeding for 24 weeks these abnormalities were sustained...

BACKGROUND AND PURPOSE Evidence of a causal relation between serum cholesterol and stroke is inconsistent. We investigated the relation between total serum cholesterol and both stroke severity and poststroke mortality to test the hypothesis that hypercholesterolemia is primarily associated with minor stroke. METHODS In the study, 652 unselected patients with ischemic stroke arrived at the hos...

BACKGROUND Statins can exert anti-inflammatory antiatherosclerotic effects through an anti-inflammatory action, independent of lowering cholesterol. We addressed the question whether the anti-inflammatory activities of statins can reduce atherosclerosis beyond the reduction achieved by cholesterol lowering per se. METHODS AND RESULTS Two groups of 20 female APOE*3-Leiden mice received either ...

The poor elderly are people aged 60 years and over, who experience socio-economic problems so they do not carry out their health checks due to limitations. This community service aims detect early in have difficulty accessing facilities detection of is carried free charge with the aim helping cannot various obstacles, held at Siti Khadijah Orphanage, Jalan Merdeka Samarinda, on September 24, 20...

Male Wistar rats were fed on a conventional diet containing normal corn starch or 6% enzyme-resistant starch originating from either raw or retrograded high-amylose corn starch. Furthermore, the diets were either cholesterol-free or contained 1% cholesterol and 0.1% cholic acid. The main objective of this study was to investigate whether the addition of enzyme-resistant starch to a rat conventi...

We investigated the time course of exercise-induced lipoprotein lipase activity (LPLa) and reverse cholesterol transport (RCT) during the 24-h postexercise period. Subjects were 10 sedentary normolipidemic males [NTG; fasting triglyceride (TG) = 89.1 +/- 8.6 mg/dl] and 6 hyperlipidemic males (HTG; fasting TG = 296.8 +/- 64.0 mg/dl). Each subject performed a control trial (no exercise) and 4 exe...

Objectives. Reduction in serum lipoproteins, especially LDL cholesterol, is a preventive approach against atherosclerosis. Bloodletting has been a recommended method to reduce serum lipoprotein concentrations. Present study was conducted to investigate the effects of wet cupping as a method of bloodletting on serum lipoproteins. In a randomized controlled trial, 47 men, 18-25 years old, without...