Maltais, François, Jean Jobin, Martin J. Sullivan, Sarah Bernard, François Whittom, Kieran J. Killian, Marc Desmeules, Marthe Bélanger, and Pierre LeBlanc. Metabolic and hemodynamic responses of lower limb during exercise in patients with COPD. J. Appl. Physiol. 84(5): 1573–1580, 1998.—Premature lactic acidosis during exercise in patients with chronic obstructive pulmonary disease (COPD) may pl...

INTRODUCTION We conducted the present study to investigate whether early large-volume crystalloid infusion can restore gut mucosal blood flow and mesenteric oxygen metabolism in severe sepsis. METHODS Anesthetized and mechanically ventilated male mongrel dogs were challenged with intravenous injection of live Escherichia coli (6 x 10(9) colony-forming units/ml per kg over 15 min). After 90 mi...

The present study retrospectively analyzed 170 patients diagnosed with paraquat (PQ) poisoning with the aim of clarifying whether the arterial lactate-time (arterial lactate concentration × time between ingestion and arterial lactate measurement) was a good predictor of mortality in patients with acute PQ poisoning. The results indicated that there was a positive correlation between the arteria...

Studies are needed to provide a rigorous examination of the relevance of monitored variables during prolonged hemorrhagic hypotension (HH). This study was designed to investigate the parameters that describe biochemical and O2 transport patterns in animals subjected to HH. Systemic parameters that could differentiate survivors from nonsurvivors were identified. An aortic flow probe was implante...

Cellular energy substrates and metabolites, electrolytes, oxygenation, and acid-base balance, in arterial and coronary sinus blood of seven adult patients who died after valvular replacements, were studied and compared with these measurements from five patients having aortic replacement who survived. Six of the patients were in New York Heart Association class IV. All but one died within 24 hr ...

Methods We have retrospectively identified septic shock patients who received protocolized treatment in two tertiary academic EDs. All patients were treated using the early goaldirected protocol. The data with respect to demographics, predisposing factors, site of infection, and the admission APACHE II score were collected. Hemodynamic (mean arterial pressure and central venous pressure) and la...

The aim of this study is to provide a systematic review of the literature reporting agreement between arterial and venous pH, partial pressure of carbon dioxide (PCO2), bicarbonate (HCO3⁻), base excess and lactate; and to perform a meta-analysis of the differences. Medline and Embase searches using Eduserv Athens from 1950 to present were conducted using the terms 'VBG', 'ABG', 'arterial', 'ven...

UNLABELLED Lactate is a key myocardial energy source. Lactate metabolism is altered in a variety of conditions, such as exercise and diabetes mellitus. However, to our knowledge, noninvasive quantitative measurements of myocardial lactate metabolism have never been performed because of the lack of an adequate radiotracer. In this study we tested L-3-(11)C-lactate ((11)C-lactate) as such a trace...

AimTo evaluate the association between lactate concentrations in fetal blood samples and different advanced labour stages.MethodsEighteen-month prospective population-based clinical study of 187 singleton pregnant women who were monitored by sampling (FBS) because non-reassuring intrapartum CTG results at Kuopio University Hospital, Finland. Peripheral concentration pH analysed stages umbilical...

Introduction: Arterial blood gases are tests that provide reliable information about the metabolic and respiratory status of patients. In traditional methods, arterial evaluated by calculating bicarbonate concentration anion gap in plasma. Since ICU patients almost always have protein electrolyte disorders, a different method has been suggested instead neglects evaluation. mathematical model de...