نتایج جستجو برای: atherosclerotic plaque

تعداد نتایج: 51806  

Journal: :Journal of the American Heart Association 2017

Journal: :Circulation: Cardiovascular Imaging 2015

Journal: :Postgraduate Medical Journal 2001

Journal: :Revista espanola de cardiologia 2006
Stephen J Nicholls Ilke Sipahi E Murat Tuzcu

Intravascular ultrasound (IVUS) has emerged as a powerful imaging modality for the assessment of the arterial wall and it's response to the accumulation of atherosclerotic plaque. The ability to image the coronary arteries on a serial basis provides a unique opportunity for IVUS to monitor the impact that potential anti-atherosclerotic strategies exert on plaque burden. As a result, studies inc...

2010
H. Chen J. Sun W. S. Kerwin N. Balu D. S. Hippe D. Isquith Y. Xue S. Peck C. Yuan K. O'Brien

Introduction Inflammation plays an important role in both atherosclerotic plaque progression and rupture [1], which has led to an interest in treatments with anti-inflammatory effects. To assess and monitor inflammation in vivo, dynamic contrast-enhanced (DCE) MRI has been previously demonstrated [2]. Kinetic parameters derived from DCE-MRI, including the transfer constant (K) and partial plasm...

2015
Tanya N. Turan Todd LeMatty Renee Martin Marc I. Chimowitz Zoran Rumboldt M. Vittoria Spampinato Seth Stalcup Robert J. Adams Truman Brown

BACKGROUND Intracranial atherosclerosis is a leading cause of stroke, but little is known about the composition of the intracranial atherosclerotic lesion and how intracranial plaque morphology is related to the risk of stroke. High-resolution magnetic resonance imaging (HR MRI) has been used in patients with extracranial carotid atherosclerosis as an in vivo tool to identify, with high-interra...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2005
Eric T Choi Emily T Collins Leopoldo A Marine Maria G Uberti Hisashi Uchida Jeremy E Leidenfrost M Faisal Khan Kenneth P Boc Dana R Abendschein William C Parks

OBJECTIVE Although matrix metalloproteinase-9 (MMP-9) has been implicated in atherosclerotic plaque instability, the exact role it plays in the plaque development and progression remains largely unknown. We generated apolipoprotein E (apoE)-deficient (apoE-/-) MMP-9-deficient (MMP-9-/-) mice to determine the mechanisms and the main cell source of MMP-9 responsible for the plaque composition dur...

Journal: :Stroke 2008
Tymen T Keller Jelger J van der Meer Peter Teeling Koen van der Sluijs Mirza M Idu Guus F Rimmelzwaan Marcel Levi Allard C van der Wal Onno J de Boer

BACKGROUND AND PURPOSE Evidence is accumulating that infection with influenza A virus contributes to atherothrombotic disease. Vaccination against influenza decreases the risk of atherosclerotic syndromes, indicating that inflammatory mechanisms may be involved. We tested the hypothesis that influenza A virus-specific T cells contribute to atherosclerotic plaque inflammation, which mediates the...

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