Many modern foam wound dressings possess a variety of attributes that are designed to create a supportive wound-healing environment. These attributes include absorbing exudate, providing optimum moisture balance at the wound surface, and preventing maceration of surrounding tissue. However, studies suggest that controlling wound bioburden should also be targeted when developing wound ther...

Antibiotic-resistant bacterial infections represent an emerging health concern in clinical settings, and a lack of novel developments in the pharmaceutical pipeline is creating a "perfect storm" for multidrug-resistant bacterial infections. Antimicrobial peptides (AMPs) have been suggested as future therapeutics for these drug-resistant bacteria, since they have potent broad-spectrum activity, ...

Article history: Received on: 16/09/2012 Revised on: 08/10/2012 Accepted on: 16/10/2012 Available online: 29/10/2012 Methanolic extracts of Lagerstroemia speciosa leaves (MLL) & barks (MBL) have been evaluated for their antimicrobial, antioxidant & cytotoxic activity. Antimicrobial activity of the extracts was evaluated against 11 Gram-positive, Gram-negative bacteria and 3 fungi using disk dif...

Antimicrobial peptides (AMPs) and their mimics are emerging as promising antibiotic agents. We present a library of "ampetoids" (antimicrobial peptoid oligomers) with helical structures and biomimetic sequences, several members of which have low-micromolar antimicrobial activities, similar to cationic AMPs like pexiganan. Broad-spectrum activity against six clinically relevant BSL2 pathogens is...

The discovery of antibiotics for the treatment of bacterial infections brought the idea that bacteria would no longer endanger human health. However, bacterial diseases still represent a worldwide treat. The ability of microorganisms to develop resistance, together with the indiscriminate use of antibiotics, is mainly responsible for this situation; thus, resistance has compelled the scientific...

Cell based therapeutics is one of the most rapidly advancing medical fields, bringing together a range of fields including transplantation, tissue engineering and regeneration, biomaterials and stem cell biology. However, traditional cell-based therapeutics have many limitations, one of which is their harmful effects exhibited on healthy body cells due to their lack of specificity. Nanomedicine...

pocket infection of a cardiac device is usually treated by removing the device and re - implanting it in a new site after complete treatment of the infection. this report illustrates a complicated case of pocket infection in the wake of the implantation of a permanent pacemaker (cardiac resynchronization therapy). the patient was treated conservatively through daily irrigation and dressing, bro...

hemophiliac patients carry a high risk for blood born viruses particularly hepatitis c virus (hcv) infection. with introducing the new therapeutic modalities for hiv infection, the role of hcv in mortality and morbidity has been more prominent. hiv co-infection is a wellknown factor that accelerates the progression of liver injury leading to end stage liver failure. screening of hemophiliacs ha...

background: cutaneous leishmaniasis (cl) is common and endemic in many areas of iran, caused by species of a protozoan parasite belonging to the genus leishmania. there is not any effective vaccine against leishmaniasis; so, therapy is important for prevention and separation of disease. herbal extract for treatment of cl is cost-effective, applicable topically to lesions, and can avoid the deve...