In recent years, adenoviruses that selectively replicate in tumor cells have been developed. However, there is a tremendous need to improve their anticancer efficacy. We wish to investigate whether a strategy that combines the oncolytic effects of an adenoviral vector with simultaneous expression of soluble form of transforming growth factor-beta type II receptor (sTGFbetaRII) offers a therapeu...

background ocular adenoviral infections occur throughout the world in both sporadic and epidemic forms. in the present study we determined the frequency of adenoviral conjunctivitis in two referral university hospitals in tehran by cell culture and pcr method. materials and methods specimens were scraped from the lower palpebral conjunctiva of 115 patients with conjunctivitis who had referred t...

In recent years, adenoviruses that selectively replicate in tumor cells have been developed. However, there is a tremendous need to improve their anticancer efficacy. We wish to investigate whether a strategy that combines the oncolytic effects of an adenoviral vector with simultaneous expression of soluble form of transforming growth factor-B type II receptor (sTGFBRII) offers a therapeutic ad...