A two-term Edgeworth expansion for the standardized version of the sample total in a two-stage sampling design is derived. In particular, for the commonly used stratified and cluster sampling schemes, formal two-term asymptotic expansions are obtained for the Studentized versions of the sample total. These results are applied in conjunction with the bootstrap to construct more accurate confiden...

The K(+) channels encoded by the human Ether-a-gogo Related Gene-1 (hERG1) are crucially involved in controlling heart and brain excitability and are selectively influenced by reactive oxygen species (ROS). To localize the molecular regions involved in ROS-induced modulation of hERG1, segmental exchanges between the ROS-sensitive hERG1 and the ROS-insensitive bovine ether-a-gogo gene (bEAG) K(+...

DNA methylation is the main epigenetic modification that occurs at the early stages of carcinogenesis. We performed a genome-wide DNA methylation profiling to evaluate whether the DNA methylation state is different in the estrogen receptor (ER) and progesterone receptor (PR) status of breast cancer. Twelve ER+/PR+ and 12 ER-/PR- breast cancer tissues were selected from the biorepository of the ...

OBJECTIVE To measure bacterial contamination rates in blood culture specimens and distinguish sepsis from blood culture contamination in newborn hospitalized patients in a neonatal intensive care unit and to recognize the most commonly isolated bacteria. MATERIALS AND METHODS Blood samples of 578 neonates were collected and cultured throughout the year of study (March 2006 to February 2007). ...

Standard discussions of perfect price discrimination rest on a hidden assumption: that the monopolist can make take-it-or-leave-it offers. If a monopoly charges different prices to each of a large number of buyers, the correct paradigm is not the ultimatum game, but bilateral monopoly. The monopolist’s profit will not be the entire surplus, but something less. Under “balanced isoperfect price d...

Processes with precisely known cross sections, like neutrino electron elastic scattering ($\nu e^{-} \!\rightarrow \nu e^{-}$) and inverse muon decay ($\nu_\mu \mu^{-} \nu_e$) have been used by MINERvA to constrain the uncertainty on NuMI beam flux. This work presents a new measurement of electrons using medium energy \numubar enhanced beam. A sample 578 events after background subtraction is i...