Genetic selection for meat production performance of broilers concomitantly causes excessive abdominal fat deposition, accompanied by several adverse effects, such as the reduction feed conversion efficiency and reproduction performance. Our previous studies have identified important genes regulating chicken using Northeast Agricultural University broiler lines divergently selected content (NEA...

Quality-by-Design (QbD) is demanded by regulatory authorities in biopharmaceutical production. Within the QbD frame advanced process control (APC), facilitated through analytical technology (PAT) and digital twins (DT), plays an increasingly important role as it can help to assure stay within predefined proven acceptable range (PAR).This ensures high product quality, minimizes failure step towa...

Stem cells have been found to reside in the different organs of the human body localized in specific niches. One such mini-organ is hair follicle wherein stem cells of epidermal origin have been reported. In the present review article we have reviewed in brief about the melanocyte stem cells of the hair follicle tissue, their identification, surface marker characteristics and role in the cell b...

The local motion adaptation at the basis of the motion aftereffect (MAE) can be expressed in a variety of ways, depending upon the structure of the test display [Wade et al. (1996). Vision Research, 36, 2167-2175]. Three experiments are reported, which examined the characteristics of the test display and of the local adaptation process. In Experiment 1, MAEs were recorded in the central of thre...

Neuronal nicotinic acetylcholine receptors (nAChRs) are in the superfamily of the ligand-gated ion channels with an assembly of five subunits (a, bsubunit). nAChRs, such as a4b-and a7-nAChRs play crucial roles in nicotine reward, dependence and withdrawal. Recently, functional profiles of the a5 nAChRs have been studied using the a5 knockout (KO) and the overexpression mice. a5-nAChRs in the b...

BACKGROUND Previous studies have shown an increased risk of stroke among patients with migraine. However, very few data are available on the possible association between chronic unspecified headache and the risk of stroke. METHODS A prospective cohort study including 35,056 randomly selected Finnish men and women aged 25 to 64 years at baseline who participated in a cardiovascular risk factor...

Aβ immunotherapy brought us not only hope for but also led to greater attention to the mechanism underlying the clearance of amyloid β (Aβ), which provided fascinating insights into disease-relevant molecules such as toxic Aβ oligomers (AβOs). Accumulated lines of evidence indicate that AβOs play a causative role in the pathogenesis of Alzheimer’s disease (AD), leading to a synaptic failure, wh...

Introduction: India is the world’s largest democratic country, and second most populous country in the world. Despite recent successes in the economic front, India still faces many social challenges like poverty, illiteracy, sanitation, gender inequality, and lack of healthcare for all. The healthcare disparity is mainly due to shortage of trained health care professionals and lack of necessary...

Tonsillectomy is old surgical procedure that has evolved to a more safe method that has lesser complications with little or no morbidity and mortality. Aim: this was comparative study which compared the old dissection tonsillectomy method and the newer method of tonsillectomy (ultrasonic scalpel and Laser tonsillectomy method). Methodology: Equal number of patients both in age and sexes had con...

Objective: To describe the most common forms of hip replacement complications that can prevail postoperatively and how obesity can impact the extent and severity of these complications. Methods: Relevant literature and research evidence concerning complications that occur after primary joint hip arthroplasty or joint replacement surgery, plus those that discussed issues of obesity in this conte...