نتایج جستجو برای: 1 glycoprotein b

تعداد نتایج: 3364606  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1985
B Seto R J Gerety

A glycoprotein was isolated and purified to homogeneity from the serum of a patient with chronic non-A, non-B hepatitis. NaDodSO4/PAGE of the glycoprotein revealed a single major band at Mr approximately 77,000. Antibodies to this glycoprotein were shown to possess the following immunoreactivity: (i) they reacted by radioimmunoassay with sera obtained at the time of diagnosis from 17 of 42 pati...

Journal: :Karger Kompass 2023

<b>Background:</b> Uveal melanoma is a disease that distinct from cutaneous melanoma, with low tumor mutational burden and 1-year overall survival of approximately 50% in patients metastatic uveal melanoma. Data showing proven benefit systemic treatment are lacking. Tebentafusp bispecific protein consisting an affinity-enhanced T-cell receptor fused to anti-CD3 effector can redirect...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Marija Backovic Richard Longnecker Theodore S Jardetzky

Epstein-Barr virus (EBV) is a herpesvirus that is associated with development of malignancies of lymphoid tissue. EBV infections are life-long and occur in >90% of the population. Herpesviruses enter host cells in a process that involves fusion of viral and cellular membranes. The fusion apparatus is comprised of envelope glycoprotein B (gB) and a heterodimeric complex made of glycoproteins H a...

Journal: :Cell 2008
Takeshi Satoh Jun Arii Tadahiro Suenaga Jing Wang Amane Kogure Junji Uehori Noriko Arase Ikuo Shiratori Shinya Tanaka Yasushi Kawaguchi Patricia G. Spear Lewis L. Lanier Hisashi Arase

Glycoprotein B (gB) is one of the essential components for infection by herpes simplex virus-1 (HSV-1). Although several cellular receptors that associate with glycoprotein D (gD), such as herpes virus entry mediator (HVEM) and Nectin-1, have been identified, specific molecules that mediate HSV-1 infection by associating with gB have not been elucidated. Here, we found that paired immunoglobuli...

Journal: :iranian journal of basic medical sciences 0
mahsa mohseni research center for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran department of medical biotechnology, faculty of advanced medical sciences, tabriz university of medical sciences, tabriz, iran nasser samadi research center for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran department of medical biotechnology, faculty of advanced medical sciences, tabriz university of medical sciences, tabriz, iran department of biochemistry and clinical laboratories, faculty of medicine, tabriz university of medical sciences, tabriz, iran parisa ghanbari research center for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran

objective(s): chemoresistance remains the main causes of treatment failure and mortality in cancer patients. there is an urgent need to investigate novel approaches to improve current therapeutic modalities and increase cancer patients' survival. induction of drug efflux due to overexpression of                  p-glycoproteins is considered as an important leading cause of multidrug resis...

Journal: :Antimicrobial Agents and Chemotherapy 2015

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