Atypical antipsychotics (AA) are generally associated with weight gain. We determined body mass index (BMI) change in Parkinson's disease (PD) before and after taking AA and compared against PD controls and Alzheimer's disease (AD) patients on AA. In 66 consecutive PD subjects started on AA who had accurate weights for more than 6 months before and after initiation of AA, we compared weight cha...

OBJECTIVE To investigate whether overweight women are more likely to have a hysterectomy and whether hysterectomy leads to increased weight gain. METHODS Survey data of middle-aged women participating in the Australian Longitudinal Study on Women's health in 1996 (ages 45-50 y; n = 13,125), 1998 (n = 10,612), 2001 (n = 10,293), and 2004 (n = 9309) included self-reported height, weight, and hy...

Topiramate was associated with weight loss in clinical trials. We summarize the evidence on the efficacy and safety of topiramate in the treatment of overweight/obesity. The databases Medline, Embase, and Cochrane were searched. Randomized controlled studies with at least 16 weeks of duration that report the effect of topiramate on weight loss and adverse events were eligible for inclusion. Ten...

conclusions alterations in consumption of whole grains, vegetables, and added sugars are associated with body weight change, suggesting that it could be helpful in weight control. results in men, weight loss was significantly predicted only by decreased intake of added sugars (or: 2.21, 95% ci: 1.06-4.63). in women, weight gain was significantly predicted by decreased intake of whole grains (or...

The aim of the present study was to examine the effects of green tea epigallocatechin-3-gallate (EGCG) on changes in body composition, energy and substrate metabolism, cardiometabolic risk factors and liver function enzymes after an energy-restricted diet intervention in obese women. In the present randomised, double-blind, placebo-controlled study, eighty-three obese (30 kg/m² > BMI < 40 kg/m²...

The title compound, C(19)H(17)N(3)O, was prepared by the 1,4-addition reaction of 1,3-di-2-pyridylprop-2-en-1-one with aniline, and includes one chiral C atom of the methine group with an R configuration. The crystal structure is stabilized by inter-molecular N-H⋯N and C-H⋯O hydrogen bonds. The crystal structure also exhibits weak inter-molecular C-H⋯π inter-actions between a pyridyl H atom and...

BACKGROUND There is a need to identify effective behavioural strategies for weight loss. Self-weighing may be one such strategy. PURPOSE To examine the effectiveness of self-weighing for weight loss. METHODS A systematic review and meta-analysis of randomised controlled trials that included self-weighing as an isolated intervention or as a component within an intervention. We used sub group...

BACKGROUND Patients with schizophrenia have lower longevity than the general population as a consequence of a combination of risk factors connected to the disease, lifestyle and the use of medications, which are related to weight gain. METHODS A multicentric, randomized, controlled-trial was conducted to test the efficacy of a 12-week group Lifestyle Wellness Program (LWP). The program consis...

BACKGROUND High fruit and vegetable intakes may limit weight gain, particularly in susceptible persons, such as those who stop smoking. OBJECTIVE The objective was to assess the association of fruit and vegetable intake with subsequent weight change in a large-scale prospective study. DESIGN The data used were from 89,432 men and women from 5 countries participating in the European Prospect...

BACKGROUND Managed care organizations (MCOs) have access to treatment and diagnosis information from administrative claims data but generally have limited or no access to clinical information about laboratory values or biometric values such as body mass index (BMI) or waist circumference. Thus, MCOs are generally unable to identify overweight patients with cardiometabolic risk factors that put ...