نتایج جستجو برای: vitamin d receptor gene
تعداد نتایج: 2112827 فیلتر نتایج به سال:
OBJECTIVES Peroxisome proliferator-activated receptor (PPAR) and vitamin D signaling pathways regulate a multitude of genes involved in different physiological functions. The aim of the present study was to examine the effects of vitamin D supplementation and aerobic training on metabolic syndrome and PPARγ expression. METHODS Forty female ovariectomized rats were divided into five groups of ...
Abstract Introduction Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory conditions of the gastrointestinal tract. Studies have shown that polymorphisms vitamin D receptor (VDR) gene may help elucidate pathogenesis CD. Objectives To analyze role VDR (ApaI, BsmI, FokI, TaqI) in development Methods The present study is a systematic review with meta-analysis. total 50 articl...
CONTEXT The vitamin D system has pleiotropic effects not only in bone metabolism. Its role in testicular steroidogenesis is new and deserves intensive research. OBJECTIVE We hypothesize that vitamin D, especially 1,25 dihydroxyvitamin D3 [1,25(OH)2D3 (calcitriol)] induces male steroidogenesis and intend to identify its impact on genes and pathways in testicular androgen regulation. METHODS ...
PURPOSE It is estimated that one third of the world's population were infected with M. tuberculosis, but only 10% of them have developed in to disease form. This subject refers to differences in host immune system activity against the tuberculosis. Vitamin D and its receptor (VDR) are important factors in the host innate immune system against the tuberculosis. In the present study VDR gene poly...
The SARS-CoV2 virus, which causes COVID-19, exerts its pathophysiological effect by intensively binding to the angiotensin-converting enzyme 2 receptor (ACE2) on host cells. By blocking ACE2 receptor, physiological functions of cell are inhibited, important for normal function various organs, and especially protection lungs. Therefore, number functionally active receptors is extremely body's re...
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