Treatment with testosterone increases proliferation of influenza virus as well as protein anabolism. A relative lack of testosterone caused by castration is associated with a diminished rate of virus growth. When protein catabolism is increased by ACTH or cortisone, the rate of virus proliferation decreases. These results suggest the existence of a correlation between alterations of protein met...

We studied the effect of ba®lomycin A1 (Baf-A1), a novel and highly speci®c inhibitor for vacuolar-type proton (V-H) pump, on the growth of Japanese Encephalitis virus (JEV) in Vero cells. Viral ̄uorescence microscopic study showed that Baf-A1 induced the complete disappearance of acidi®ed compartments such as endosomes and lysosomes in Vero cells by the treatment with 0.1 mM Baf-A1 for 1 h at 3...

The human herpes virus Epstein-Barr virus (EBV) latently infects and drives the proliferation of B lymphocytes in vitro and is associated with several forms of lymphoma and carcinoma in vivo. The virus encodes ~30 miRNAs in the BART region, the function of most of which remains elusive. Here we have used a new mouse xenograft model of EBV driven carcinomagenesis to demonstrate that the BART miR...