The patient was first seen at the age of 4 years 2 months because of persistent vomiting and failure to thrive. She was born in July 1965 at 38 weeks gestation after an uncomplicated pregnancy and a normal delivery; the birthweight was 2818 g. She was the eldest of four sibs of unrelated healthy parents aged 24 (father) and 22 years (mother) at the time of her birth. The mother had no known mis...

By CEsAR REYNAFARJE AND JOSE RAMOS H UMAN bartonellosis, or Carrion’s disease, is characterized by rapid development of severe hemolytic anemia in the acute stage of the disease caused by infestation of the erythrocytes by Bartonella bacilliformis. The bacterium described by Barton’ in 1905 is visible in the red cells at the acute stage, so that their examination makes the diagnosis very easy (...

Considerations regarding the etiology of hemolytic jaundice are inextricably bound up with the presence of spherocytosis and the associated increase in hypotonic saline fragility, and the effect of splenectomy in the amelioration of this disorder. Although many different opinions are advanced regarding the etiology of the disease, the outstanding ones are those postulating a faulty bone marrow ...

Objective: To investigate the clinical features and genetic characteristics of cases with X-linked immunodeficiency with magnesium defect, Epstein-Barr virus (EBV) infection, and neoplasia (XMEN). Methods: Characteristics of clinical material, immunological data and gene mutation of two cases with XMEN in the same family in China were retrospectively analyzed. The related reports literature wer...

The role of hem&in in hemoglobin and bile pigment metabolism is not clearly defined. Opinion has been divided over the questions of whether or not hematin is a normal degradation product of hemoglobin and whether or not it is converted to bile pigment. Bingold observed that the occurrence of hen&in in the plasma is associated with a variety of pathologic conditions (1). The conditions in which ...

ont matter & 2005 2005.10.002 thor. Tel.: +1 718 . howdhur@aecom. Summary Bilirubin is the breakdown product of the haem moiety of haemoglobin and other haemoproteins. Because of internal hydrogen bonding, bilirubin is water-insoluble and requires enzyme-mediated glucuronidation in the liver for biliary excretion. In normal circumstances, plasma bilirubin is mostly unconjugated and is tightly b...

he occasional occurrence of chronic intravascu lar hemolysis following cardiac prosthetic sur gery is well documented.1 In this syndrome the pathophysiologic sequence of events has been postulated to occur as follows: turbulence from val vular deformity fragments erythrocytes and induces intravascular hemolysis. If severe, the resulting anemia increases both cardiac output and turbu lence. Long...

Aksoy, M., DinVol, K., Erdem, S., Akgiin, T., and Diniol, G. (1972). Brit. J. industr. Med., 29, 56-64. Details of blood changes in 32 patients with pancytopenia associated with long-term exposure to benzene. A study was performed on 32 pancytopenic patients who had had longterm exposure to benzene. They had been subjected to high concentrations of benzene varying from 150 to 650 p.p.m. for fro...

Dr. Rebecca C. Bell (Pediatrics): A 6-day-old boy was admitted to this hospital because of vomiting, diarrhea, and abdominal distention. The patient was born at another hospital to a teenaged primigravida by vaginal delivery after a full-term, uncomplicated gestation. The mother had received prenatal care; she had no history of sexually transmitted infections, and prenatal screening tests were ...

SI NCE THE ORIGINAL report by Harris et al.' in 1956, six additional I)ttients with anemia responsive to the administration of pyrinioxine have been described.27 With the exception of the case reported by Maier,2 tile features which have been common to this group of patients hiave I)een micro-cytic, hypochromic anemia, hyperferremia, hemosidlerosis and a partial or complete response of the anem...