CUP syndrome (cancer of unknown primary) describes the presence histologically proven metastases in an primary tumor. It affects about 3–5% all tumor patients. The search for makes extensive diagnostics necessary. However, 2/3 patients original is not discovered. Operation, radiation, chemotherapy and, some cases, targeted therapy are available as treatment. prognosis unfavorable.

abstract liver neoplasm is not an uncommon disease in asian countries. liposarcoma is a rare mesenchymal malignant tumor which usually originates in the retroperitoneum and extremities. from 1973 till now about 10 cases of primary liver liposarcoma have been reported. we present the eleventh case in a young adult female with uncommon presentation. she suffered from a huge mass in the right port...

Die Medizin wird von evidenzbasierten Standards dominiert: Therapieschemata werden Diagnosen zugeordnet – Patienten gleicher Diagnose werden mit gleicher Medizin behandelt. Ziel der dreidimensionalen Tumordokumentation und Therapieplanung ist eine Individualisierung der Diagnostik und somit auch eine individuellere Therapieplanung. Der TTM Tumor Therapy Manager ist ein erstes in der klinischen ...

The periodical application of androgen deprivation therapy, immunotherapy, or chemotherapy is an effective method for cancer treatment, but few studies combine them. To explore such comprehensive treatment mechanisms, this paper establishes a pulsed stochastic hybrid dynamics model considering tumor antigenicity and density-dependent mortality. In addition to analyzing the basic properties solu...

Combination chemotherapy is widely exploited to overcome multidrug resistance (MDR) and enhance the therapeutic effect of anti-tumor agents clinically. The traditional combination regimens applied in clinical practice still suffer from various obstacles, such as inevitable side effects. Fortunately, application nanotechnology proposal co-delivery systems make therapy more effective. occurrence,...

  Purpose: To recognize affective factors in delivering X-ray contrast agents (which have high atomic number) via gallium carrier to liver or lymphatic neoplasm cells.   Materials and Methods: Since uptake of gallium by liver has been reported in numerous researches, it was bonded with a contrast media (metrizoate). X-ray imaging was done to determine geometric features of liver.   Results: Rad...

This perspective systematically summarizes the latest research progress of metal ion-based anti-tumor therapy, and emphasizes challenges development directions this type therapeutic strategy.