Intradural extramedullary tuberculoma of the spinal cord (IETSC) is an uncommon disease which can occurs secondary to tuberculous meningitis. A 31-year-old woman was diagnosed as tuberculous meningitis after mental disorientation. Her mentality was recovered after antituberculous therapy. After 7 months of antituberculous therapy, paraplegia has developed. Magnetic resonance imaging (MRI) revea...

tuberculous meningitis treatment: Results of Haydarpasa-3 Study Hakan Erdem; Derya Ozturk-Engin; Serap Gencer; Oral Oncul Professor; Hanefi Cem Gul,; Haluk Vahaboglu; Gata Haydarpasa Training Hospital, Infectious Disease and Clinical Microbiology Deparment, Istanbul, Turkey; Haydarpasa Numume Training Hospital, Istanbul, Turkey; Department of Infectious Diseases and Clinical Microbiology, Lutfi...

When isoniazid is used for the chemotherapy of tuberculous meningitis the need for intrathecal therapy is controversial. A Scottish Joint Committee (1957) concluded from a comparative trial, including both adults and children, that intrathecal streptomycin is not now an essential part of the treatment. But, in fact, all the patients reported did receive intrathecal streptomycin for at least one...

Tuberculous meningitis and meningoencephalitis are rare and dangerous complications of infections with mycobacteria-complex. Usually these are complications of systemic florid infection with Mycobacterium (M.) tuberculosis. They are most often seen in immune compromised patients. The confirmation of diagnosis can be elaborate and delayed due to long-term culture requirements for M. tuberculosis...

Tuberculous meningitis is an important global medical problem which gives rise to high morbidity and mortality. It is the most severe form of extrapulmonary Mycobacterium tuberculosis. Comprehensive prevention effort, prompt diagnosis and rational treatment are all keys to improving treatment outcomes; yet many unsolved problems remain. On the other hand, the new problems, such as HIV co-infect...

In January, 1944, Schatz, Bugie, and Waksman' reported the isolation of a new antibacterial substance which was designated as streptomycin. In December, 1944, Feldman and Hinshaw' reported their observations on the suppressive effect of streptomycin on the human variety of microbacterium tuberculosis in guinea pigs. In January, 1946, Cooke, Dunphy, and Blake' reported in this Journal the first ...

One of the commonest causes of failure in the treatment of tuberculous meningitis by streptomycin is the formation of intracranial and intraspinal adhesions with resultant hydrocephalus. These adhesions are produced par-tly as a result of the fibroblastic reaction that occurs around tuberculous foci, but their inception and growth may well be stimulated by the deposition of fibrin from the cere...

Tuberculous meningitis leads to a high mortality rate. However, it responds well to chemotherapy if the treatment is started early. Neuroimaging is one of the most important initial investigations. There were 42 patients diagnosed with tuberculous meningitis in Kuala Lumpur Hospital based on clinical criteria, cerebrospinal fluid analysis and response to anti-tuberculous treatment over a 7 year...

is in the vicinity of 5,000 blood donations annually, apart from the cost of the associated equipment for the preparation of platelet concentrates and the salary of a technologist over and above the salaries of the blood collection staff necessary. In this country we have available a "mini-exchange" set,3 comprising a needle and tubing connected to one limb of a Ypiece which has a free length o...

Central nervous system tuberculosis may present as commonly encountered tuberculous meningitis or tuberculous mass lesions [common tuberculoma, and rare tuberculous brain abscess (TB-Abs)]. TB-Abs was first described by Evans and Rand (early 1930s), and is still very rare in world literature. This rare case report serves as a reminder for tuberculosis as etiology of brain abscess in a HIV-negat...