Recently, supercritical fluid extraction (SFE) has been indicated to be utilized as part of a biorefinery, rather than as a stand-alone technology, since besides extracting added value compounds selectively it has been shown to have a positive effect on the downstream processing of biomass. To this extent, this work evaluates economically the encouraging experimental results regarding the use o...

The NF-kB transcription factor functions as a crucial regulator of cell survival and chemoresistance in pancreatic cancer. Recent studies suggest that tocotrienols, which are the unsaturated forms of vitamin E, are a promising class of anticancer compounds that inhibit the growth and survival of many cancer cells, including pancreatic cancer. Here, we show that tocotrienols inhibited NF-kB acti...

The content and composition of different vitamin E isoforms was analyzed in normal human skin. Interestingly the epidermis contained 1% alpha-tocotrienol, 3% gamma-tocotrienol, 87% alpha-tocopherol, and 9% gamma-tocopherol. Although the levels of tocotrienol in human epidermis appear to be considerably lower than reported in the hairless mouse, the presence of significant amounts of tocotrienol...

Several important nutraceutical compounds, such as tocotrienols, tocopherols, and oryzanols, can be extracted from rice bran, a by-product of milling. This study was conducted to not only provide information regarding nutraceutical concentrations within the rice kernel based on bran collected from successive milling, but also to determine levels of nutraceutical concentrations across several di...

509 The rice bran oil (RBO) contains high levels of phytosterols, gammaoryzanol, tocotrienols as well as tocopherols and it extends the shelf-life of snack foods. The high oxidative stability of RBO makes it preferred oil for frying and baking applications. The saturated, monounsaturated and polyunsaturated fatty acids in RBO are in the ratio of approximately 1:2.2:1.5 and the major fatty acid ...

CONTEXT Preliminary studies have suggested that both citrus flavonoids and palm tocotrienols reduce cholesterol levels in laboratory animals. OBJECTIVE To examine the effect of these nutrients in combination on blood levels of cholesterol and related cardiovascular disease risk factors. DESIGN Two open-label studies and 1 double-blind study are reported. SETTING Outpatient clinical resear...

Ageing is a nonmodifiable risk factor that is linked to increased likelihood of cardiovascular morbidities. Whilst many pharmacological interventions currently exist to treat many of these disorders such as statins for hypercholesterolemia or beta-blockers for hypertension, the elderly appear to present a greater likelihood of suffering non-related side effects such as increased risk of develop...

Parboiled rice bran oil was obtained using supercritical CO2 under different conditions of temperature (2°C to 40°C) and pressure (25 to 200 bar). In this study the experiments were carried out with two separators coupled to the extractor. The temperature levels in the first separator were 25°C and 40°C and in the second it was maintained constant at 2°C. The pressures in the first separator we...

0308-8146/$ see front matter Published by Elsevier doi:10.1016/j.foodchem.2010.01.057 * Tel.: +1 808 959 4343. E-mail address: [email protected] Phytochemical compounds (tocopherols, tocotrienols, and squalene) were measured in seven macadamia cultivars harvested from four locations on Hawaii island to establish whether these compounds enhance the oxidative stability of roasted kernels. ...

Wheat is a major component within human consumption, and due to the large intake of wheat, it has an impact on human nutritional health. This study aimed at an increased understanding of how the content and composition of tocols may be governed for increased nutritional benefit of wheat consumption. Therefore, ten South African wheat cultivars from three locations were fractionated into white a...