نتایج جستجو برای: thalassemic

تعداد نتایج: 1036  

Journal: :Blood 1994
J Carlson G B Nash V Gabutti F al-Yaman M Wahlgren

Genes for two lethal diseases, thalassemia and sickle cell anemia, are favored by evolution because, in their heterozygous form, they protect against cerebral malaria. Rosette formation, the binding of uninfected red cells (RBCs) to Plasmodium falciparum-infected RBCs (PRBCs), has previously been found to be associated with cerebral malaria, the most important severe manifestation of P falcipar...

Journal: :international journal of hematology-oncology and stem cell research 0
ebrahim miri-moghaddam genetics of non-communicable disease research centre, zahedan university of medical sciences, zahedan, iran ; department of genetics, zahedan university of medical sciences, zahedan, iran. narjes sargolzaie department of community medicine, zahedan university of medical sciences, zahedan, iran.

objective: the two most frequent hypochromic microcytic anemias are β- thalassemia minor (btm) and iron deficiency anemia (ida). several discrimination indices have been proposed to quickly discriminate these similar entities via parameters obtained from automated blood count analyzers. the aim of this study to evaluate the diagnostic reliability of ten discrimination indices in the differentia...

Journal: :Imaging Journal of Clinical and Medical Sciences 2016

Journal: :Revista latino-americana de enfermagem 2011
Marcela Ganzella Márcia Maria Fontão Zago

This study, based on medical anthropology and oral reports, analyzes the meanings attributed by thalassemic adults to their experiences with the treatment. Interviews were used to collect data, which were analyzed through inductive thematic analysis. Eleven young adults, six of whom were men, at different ages, with different educational levels and occupations participated in the study. The mea...

Journal: :Urologia internationalis 2007
V Savica D Santoro P Monardo F Ciolino A Magistro A Blandino G Bellinghieri

We report the case of a 13-year-old male patient with beta-thalassemic trait who presented for a colic pain. An ultrasound of the abdomen revealed absence of the right kidney with a complex hypoechogenic pelvic mass causing mild pressure on the posterior bladder wall. Urography showed hypertrophy of the left kidney with moderate ureteral enlargement of the distal third due to an insertion defec...

Journal: :Free radical research 2006
L Tesoriere M Allegra D Butera C Gentile M A Livrea

Antioxidant phytochemicals are investigated as novel treatments for supportive therapy in beta-thalassemia. The dietary indicaxanthin was assessed for its protective effects on human beta-thalassemic RBCs submitted in vitro to oxidative haemolysis by cumene hydroperoxide. Indicaxanthin at 1.0-10 microM enhanced the resistance to haemolysis dose-dependently. In addition, it prevented lipid and h...

1999
Kovit Pattanapanyasat Kosol Yongvanitchit Pongsri Tongtawe Kalaya Tachavanich Wanchai Wanachiwanawin Suthat Fucharoen Douglas S. Walsh

Certain red blood cell (RBC) disorders, including thalassemia, have been associated with an innate protection against malaria infection. However, many in vitro correlative studies have been inconclusive. To better understand the relationship between human RBCs with thalassemia hemoglobinopathies and susceptibility to in vitro infection, we used an in vitro coculture system that involved biotin ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1971
D G Nathan H F Lodish Y W Kan D Housman

To define the quality and relative quantity of beta and alpha messenger RNA in human nonthalassemic and thalassemic reticulocytes, intact cells were incubated with [(35)S]methionine. The relative amounts of beta- and alpha-nascent chains on polysomes of different sizes were measured by tryptic digestion of pooled polysomes and by determination of the specific activities of beta and alpha peptid...

Journal: :Journal of Parathyroid Disease 2023

Thalassemia is a hematological disorder caused by gene mutation that leads to defective synthesis of hemoglobin complex. One the complications thalassemia hypocalcemia which presented with paresthesia, muscle spasm, low-serum calcium, and intracranial calcification. Hypocalcemia can affect thalassemic patients via various mechanisms. Blood transfusion-related transfusion-independent iron overlo...

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